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    Cdk2ap2 CDK2-associated protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 52004, updated on 5-Feb-2019

    Summary

    Official Symbol
    Cdk2ap2provided by MGI
    Official Full Name
    CDK2-associated protein 2provided by MGI
    Primary source
    MGI:MGI:1098779
    See related
    Ensembl:ENSMUSG00000024856
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Doc-1r; D19Ertd144e; 5830466O21Rik
    Expression
    Ubiquitous expression in duodenum adult (RPKM 135.5), adrenal adult (RPKM 120.9) and 27 other tissues See more
    Orthologs

    Genomic context

    See Cdk2ap2 in Genome Data Viewer
    Location:
    19; 19 A
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (4096894..4099019)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (4097351..4099017)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 42060 Neighboring gene calcium binding protein 2 Neighboring gene phosphatidylinositol transfer protein, membrane-associated 1 Neighboring gene aryl-hydrocarbon receptor-interacting protein Neighboring gene transmembrane protein 134

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    negative regulation of G1/S transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of microtubule cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of stem cell division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    microtubule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    cyclin-dependent kinase 2-associated protein 2
    Names
    DOC-1 related protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026373.4NP_080649.1  cyclin-dependent kinase 2-associated protein 2

      See identical proteins and their annotated locations for NP_080649.1

      Status: VALIDATED

      Source sequence(s)
      AC109138
      Consensus CDS
      CCDS29414.1
      UniProtKB/Swiss-Prot
      Q9CPY4
      Related
      ENSMUSP00000025779.4, ENSMUST00000025779.10
      Conserved Domains (2) summary
      pfam09806
      Location:74126
      CDK2AP; Cyclin-dependent kinase 2-associated protein
      cl28408
      Location:5107
      UBQ; Ubiquitin homologues

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

      Range
      4096894..4099019
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531787.3XP_006531850.1  cyclin-dependent kinase 2-associated protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006531850.1

      Conserved Domains (1) summary
      pfam09806
      Location:54106
      CDK2AP; Cyclin-dependent kinase 2-associated protein

    Reference GRCm38.p4 PATCHES

    Genomic

    1. NW_004058054.1 Reference GRCm38.p4 PATCHES

      Range
      83366..85032
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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