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    Fubp1 far upstream element (FUSE) binding protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 51886, updated on 31-Jan-2019

    Summary

    Official Symbol
    Fubp1provided by MGI
    Official Full Name
    far upstream element (FUSE) binding protein 1provided by MGI
    Primary source
    MGI:MGI:1196294
    See related
    Ensembl:ENSMUSG00000028034
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    FBP; Fubp; Fubp4; D3Ertd330e; 9530027K12Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 43.8), CNS E14 (RPKM 43.1) and 27 other tissues See more
    Orthologs

    Genomic context

    See Fubp1 in Genome Data Viewer
    Location:
    3 H3; 3 77.05 cM
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (152210427..152236830)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (151873422..151899794)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 31881 Neighboring gene GIPC PDZ domain containing family, member 2 Neighboring gene predicted gene, 40179 Neighboring gene DnaJ heat shock protein family (Hsp40) member B4 Neighboring gene predicted gene, 40180 Neighboring gene nexilin Neighboring gene predicted gene, 31999

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (2) 
    • Targeted (1)  1 citation
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription activator activity, RNA polymerase II-specific IDA
    Inferred from Direct Assay
    more info
    PubMed 
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    sequence-specific double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    developmental cell growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    hematopoietic stem cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of Schwann cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    somatic stem cell division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    far upstream element-binding protein 1
    Names
    FUSE-binding protein 1
    far upstream element (FUSE) binding protein 4

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355366.1NP_001342295.1  far upstream element-binding protein 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC123075
      Conserved Domains (2) summary
      cd00105
      Location:295356
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:119183
      KH_1; KH domain
    2. NM_001355367.1NP_001342296.1  far upstream element-binding protein 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC123075
      Conserved Domains (2) summary
      cd00105
      Location:294355
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:118182
      KH_1; KH domain
    3. NM_001355368.1NP_001342297.1  far upstream element-binding protein 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC123075
      Conserved Domains (2) summary
      cd00105
      Location:295356
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:119183
      KH_1; KH domain
    4. NM_001355369.1NP_001342298.1  far upstream element-binding protein 1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC123075
      Conserved Domains (2) summary
      cd00105
      Location:274335
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:98162
      KH_1; KH domain
    5. NM_001355370.1NP_001342299.1  far upstream element-binding protein 1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC123075
      Conserved Domains (2) summary
      cd00105
      Location:273334
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:97161
      KH_1; KH domain
    6. NM_001355371.1NP_001342300.1  far upstream element-binding protein 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC123075
      Conserved Domains (2) summary
      cd00105
      Location:274335
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:98162
      KH_1; KH domain
    7. NM_001355372.1NP_001342301.1  far upstream element-binding protein 1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC123075
      Conserved Domains (2) summary
      cd00105
      Location:274335
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:98162
      KH_1; KH domain
    8. NM_001355373.1NP_001342302.1  far upstream element-binding protein 1 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC123075
      Conserved Domains (2) summary
      cd00105
      Location:274335
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:98162
      KH_1; KH domain
    9. NM_001355374.1NP_001342303.1  far upstream element-binding protein 1 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC123075
      Conserved Domains (2) summary
      cd00105
      Location:273334
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:97161
      KH_1; KH domain
    10. NM_057172.4NP_476513.2  far upstream element-binding protein 1 isoform 8

      See identical proteins and their annotated locations for NP_476513.2

      Status: VALIDATED

      Source sequence(s)
      AC123075, AK028418
      Consensus CDS
      CCDS38672.1
      UniProtKB/TrEMBL
      Q3TUE1
      Related
      ENSMUSP00000130145.1, ENSMUST00000166984.7
      Conserved Domains (2) summary
      cd00105
      Location:97159
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam09005
      Location:606620
      DUF1897; Domain of unknown function (DUF1897)

    RNA

    1. NR_149713.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC123075, AK138011

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      152210427..152236830
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319639.1XP_017175128.1  far upstream element-binding protein 1 isoform X9

      Conserved Domains (2) summary
      cd00105
      Location:273334
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:97161
      KH_1; KH domain
    2. XM_017319640.1XP_017175129.1  far upstream element-binding protein 1 isoform X14

      Related
      ENSMUSP00000143370.1, ENSMUST00000198227.4
      Conserved Domains (2) summary
      cd00105
      Location:273334
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:97161
      KH_1; KH domain
    3. XM_006501672.1XP_006501735.1  far upstream element-binding protein 1 isoform X11

      Conserved Domains (2) summary
      cd00105
      Location:97159
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam09005
      Location:603617
      DUF1897; Domain of unknown function (DUF1897)
    4. XM_006501663.1XP_006501726.1  far upstream element-binding protein 1 isoform X3

      Conserved Domains (2) summary
      cd00105
      Location:119181
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam09005
      Location:628642
      DUF1897; Domain of unknown function (DUF1897)
    5. XM_006501666.1XP_006501729.1  far upstream element-binding protein 1 isoform X5

      Conserved Domains (2) summary
      cd00105
      Location:295356
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:119183
      KH_1; KH domain
    6. XM_006501664.1XP_006501727.1  far upstream element-binding protein 1 isoform X4

      Conserved Domains (2) summary
      cd00105
      Location:119181
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam09005
      Location:628642
      DUF1897; Domain of unknown function (DUF1897)
    7. XM_006501660.1XP_006501723.1  far upstream element-binding protein 1 isoform X1

      Conserved Domains (2) summary
      cd00105
      Location:119181
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam09005
      Location:628642
      DUF1897; Domain of unknown function (DUF1897)
    8. XM_006501669.1XP_006501732.1  far upstream element-binding protein 1 isoform X7

      Conserved Domains (2) summary
      cd00105
      Location:295356
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:119183
      KH_1; KH domain
    9. XM_006501662.1XP_006501725.1  far upstream element-binding protein 1 isoform X2

      Conserved Domains (2) summary
      cd00105
      Location:119181
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam09005
      Location:625639
      DUF1897; Domain of unknown function (DUF1897)
    10. XM_017319638.1XP_017175127.1  far upstream element-binding protein 1 isoform X6

      Conserved Domains (2) summary
      cd00105
      Location:294355
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:118182
      KH_1; KH domain
    11. XM_006501670.1XP_006501733.1  far upstream element-binding protein 1 isoform X8

      UniProtKB/TrEMBL
      A0A0G2JFY5
      Related
      ENSMUSP00000143354.1, ENSMUST00000200524.4
      Conserved Domains (2) summary
      cd00105
      Location:274335
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:98162
      KH_1; KH domain
    12. XM_006501673.1XP_006501736.1  far upstream element-binding protein 1 isoform X12

      UniProtKB/TrEMBL
      A0A0G2JGW9
      Related
      ENSMUSP00000143729.1, ENSMUST00000196695.4
      Conserved Domains (2) summary
      cd00105
      Location:274335
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:98162
      KH_1; KH domain
    13. XM_006501671.1XP_006501734.1  far upstream element-binding protein 1 isoform X10

      UniProtKB/Swiss-Prot
      Q91WJ8
      Related
      ENSMUSP00000143101.1, ENSMUST00000196739.4
      Conserved Domains (2) summary
      cd00105
      Location:274335
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:98162
      KH_1; KH domain
    14. XM_006501674.1XP_006501737.1  far upstream element-binding protein 1 isoform X13

      UniProtKB/TrEMBL
      Q0P6B2
      Conserved Domains (2) summary
      cd00105
      Location:274335
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam00013
      Location:98162
      KH_1; KH domain

    RNA

    1. XR_001783710.1 RNA Sequence

    2. XR_001783712.1 RNA Sequence

    3. XR_001783705.1 RNA Sequence

    4. XR_001783706.1 RNA Sequence

    5. XR_375543.3 RNA Sequence

    6. XR_001783714.1 RNA Sequence

    7. XR_375541.1 RNA Sequence

    8. XR_001783708.1 RNA Sequence

    9. XR_001783709.1 RNA Sequence

    10. XR_001783713.1 RNA Sequence

    11. XR_001783707.1 RNA Sequence

    12. XR_375540.1 RNA Sequence

      Related
      ENSMUST00000199876.4
    13. XR_001783711.1 RNA Sequence

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