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    Ctps cytidine 5'-triphosphate synthase [ Mus musculus (house mouse) ]

    Gene ID: 51797, updated on 18-Nov-2018

    Summary

    Official Symbol
    Ctpsprovided by MGI
    Official Full Name
    cytidine 5'-triphosphate synthaseprovided by MGI
    Primary source
    MGI:MGI:1858304
    See related
    Ensembl:ENSMUSG00000028633 Vega:OTTMUSG00000008810
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ctps1
    Expression
    Broad expression in CNS E11.5 (RPKM 19.6), bladder adult (RPKM 15.5) and 24 other tissues See more
    Orthologs

    Genomic context

    See Ctps in Genome Data Viewer
    Location:
    4 D2.2; 4 56.52 cM
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (120539868..120570276, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (120212473..120242881, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene sex comb on midleg homolog 1 Neighboring gene schlafen like 1 Neighboring gene predicted gene 8439 Neighboring gene predicted gene, 29891

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    CTP synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    CTP synthase activity ISO
    Inferred from Sequence Orthology
    more info
     
    identical protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    B cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    CTP biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    CTP biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    T cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    glutamine metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    pyrimidine nucleobase biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    pyrimidine nucleotide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoophidium IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoophidium ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    CTP synthase 1
    Names
    CTP synthetase 1
    UTP--ammonia ligase 1
    NP_058028.2
    XP_006503288.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355491.1NP_001342420.1  CTP synthase 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK148259, AK161110, AL611924, CD363725
      Conserved Domains (1) summary
      PLN02327
      Location:1556
      PLN02327; CTP synthase
    2. NM_016748.2NP_058028.2  CTP synthase 1

      See identical proteins and their annotated locations for NP_058028.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant represents the shorter transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK146476, AK148259, AK161110, CD363725
      Consensus CDS
      CCDS18591.1
      UniProtKB/Swiss-Prot
      P70698
      Related
      ENSMUSP00000030381.7, OTTMUSP00000009199, ENSMUST00000030381.7, OTTMUST00000020056
      Conserved Domains (1) summary
      PLN02327
      Location:1556
      PLN02327; CTP synthase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      120539868..120570276 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006503225.3XP_006503288.1  CTP synthase 1 isoform X1

      UniProtKB/Swiss-Prot
      P70698
      Conserved Domains (1) summary
      PLN02327
      Location:1556
      PLN02327; CTP synthase
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