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    Ppp2r1a protein phosphatase 2, regulatory subunit A, alpha [ Mus musculus (house mouse) ]

    Gene ID: 51792, updated on 5-Sep-2021

    Summary

    Official Symbol
    Ppp2r1aprovided by MGI
    Official Full Name
    protein phosphatase 2, regulatory subunit A, alphaprovided by MGI
    Primary source
    MGI:MGI:1926334
    See related
    Ensembl:ENSMUSG00000007564
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    P; PR; PP2A; PR65; 6330556D22Rik
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 147.1), CNS E18 (RPKM 140.4) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ppp2r1a in Genome Data Viewer
    Location:
    17; 17 A3.2
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (21165716..21186167)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (20945454..20965905)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (21082418..21102869)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 1 receptor 232 Neighboring gene vomeronasal 1 receptor, pseudogene 144 Neighboring gene vomeronasal 1 receptor, pseudogene 145 Neighboring gene vomeronasal 1 receptor 233

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein antigen binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein heterodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein phosphatase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein serine/threonine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, centromeric region ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in glutamatergic synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of protein phosphatase type 2A complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of protein phosphatase type 2A complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of protein phosphatase type 2A complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
    Names
    protein phosphatase PP2A
    serine/threonine protein phosphatase A subunit type 2A
    NP_058587.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_016891.3NP_058587.1  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

      See identical proteins and their annotated locations for NP_058587.1

      Status: PROVISIONAL

      Source sequence(s)
      AC109204
      Consensus CDS
      CCDS28432.1
      UniProtKB/Swiss-Prot
      Q76MZ3
      Related
      ENSMUSP00000007708.8, ENSMUST00000007708.14
      Conserved Domains (3) summary
      COG1413
      Location:187462
      HEAT; HEAT repeat [General function prediction only]
      sd00044
      Location:245269
      HEAT; HEAT repeat [structural motif]
      pfam02985
      Location:166196
      HEAT; HEAT repeat

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      21165716..21186167
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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