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    Ppp2r1a protein phosphatase 2, regulatory subunit A, alpha [ Mus musculus (house mouse) ]

    Gene ID: 51792, updated on 16-Nov-2018

    Summary

    Official Symbol
    Ppp2r1aprovided by MGI
    Official Full Name
    protein phosphatase 2, regulatory subunit A, alphaprovided by MGI
    Primary source
    MGI:MGI:1926334
    See related
    Ensembl:ENSMUSG00000007564 Vega:OTTMUSG00000016281
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PP2A; PR65; 6330556D22Rik
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 147.1), CNS E18 (RPKM 140.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ppp2r1a in Genome Data Viewer
    Location:
    17; 17 A3.2
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (20945454..20965905)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (21082418..21102869)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene vomeronasal 1 receptor 232 Neighboring gene vomeronasal 1 receptor, pseudogene 144 Neighboring gene vomeronasal 1 receptor, pseudogene 145 Neighboring gene vomeronasal 1 receptor 233

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein antigen binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein heterodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphatase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to protein serine/threonine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein serine/threonine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    chromosome, centromeric region ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    glutamatergic synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    protein phosphatase type 2A complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein phosphatase type 2A complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein phosphatase type 2A complex ISO
    Inferred from Sequence Orthology
    more info
     
    synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
    Names
    PP2A subunit A isoform PR65-alpha
    PP2A subunit A isoform R1-alpha
    protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
    protein phosphatase PP2A
    serine/threonine protein phosphatase A subunit type 2A
    NP_058587.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_016891.3NP_058587.1  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

      See identical proteins and their annotated locations for NP_058587.1

      Status: PROVISIONAL

      Source sequence(s)
      AC109204
      Consensus CDS
      CCDS28432.1
      UniProtKB/Swiss-Prot
      Q76MZ3
      Related
      ENSMUSP00000007708.7, OTTMUSP00000017454, ENSMUST00000007708.13, OTTMUST00000039080
      Conserved Domains (2) summary
      sd00044
      Location:245269
      HEAT; HEAT repeat [structural motif]
      cl26104
      Location:187462
      HEAT_2; HEAT repeats

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      20945454..20965905
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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