Format

Send to:

Choose Destination
    • Showing Current items.

    Hs6st1 heparan sulfate 6-O-sulfotransferase 1 [ Mus musculus (house mouse) ]

    Gene ID: 50785, updated on 23-May-2018

    Summary

    Official Symbol
    Hs6st1provided by MGI
    Official Full Name
    heparan sulfate 6-O-sulfotransferase 1provided by MGI
    Primary source
    MGI:MGI:1354958
    See related
    Ensembl:ENSMUSG00000045216 Vega:OTTMUSG00000029555
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6Ost1
    Expression
    Ubiquitous expression in adrenal adult (RPKM 91.8), kidney adult (RPKM 52.1) and 27 other tissues See more
    Orthologs

    Genomic context

    See Hs6st1 in Genome Data Viewer
    Location:
    1; 1 B
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (36068400..36106446)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (36125245..36163291)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 39623 Neighboring gene predicted gene, 39624 Neighboring gene predicted gene, 33280 Neighboring gene microRNA 6897 Neighboring gene UDP-glucose glycoprotein glucosyltransferase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    heparan sulfate 6-O-sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    heparan sulfate 6-O-sulfotransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    sulfotransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    heparan sulfate proteoglycan biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    heparan sulfate proteoglycan biosynthetic process, enzymatic modification IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    heparan sulfate proteoglycan biosynthetic process, enzymatic modification IDA
    Inferred from Direct Assay
    more info
    PubMed 
    labyrinthine layer blood vessel development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    lung alveolus development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neuron development ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    heparan-sulfate 6-O-sulfotransferase 1
    Names
    HS6ST-1
    mHS6ST-1
    NP_056633.2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_015818.2NP_056633.2  heparan-sulfate 6-O-sulfotransferase 1

      See identical proteins and their annotated locations for NP_056633.2

      Status: VALIDATED

      Source sequence(s)
      AI182294, BC052316
      Consensus CDS
      CCDS48237.1
      UniProtKB/Swiss-Prot
      Q9QYK5
      Related
      ENSMUSP00000085499.3, OTTMUSP00000037912, ENSMUST00000088174.3, OTTMUST00000073283
      Conserved Domains (2) summary
      pfam03567
      Location:85350
      Sulfotransfer_2; Sulfotransferase family
      pfam14878
      Location:328402
      DLD; Death-like domain of SPT6

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      36068400..36106446
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center