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    Fbxw14 F-box and WD-40 domain protein 14 [ Mus musculus (house mouse) ]

    Gene ID: 50757, updated on 5-Aug-2018

    Summary

    Official Symbol
    Fbxw14provided by MGI
    Official Full Name
    F-box and WD-40 domain protein 14provided by MGI
    Primary source
    MGI:MGI:1354703
    See related
    Ensembl:ENSMUSG00000105589 Vega:OTTMUSG00000027444
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fbx12; Fbxo12; AU045528; E330009N23Rik
    Expression
    Restricted expression toward ovary adult (RPKM 1.2) See more

    Genomic context

    See Fbxw14 in Genome Data Viewer
    Location:
    9; 9 F2
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (109270975..109287729, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (109173639..109190190, complement)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene F-box and WD-40 domain protein 13 Neighboring gene F-box and WD-40 domain protein 20 Neighboring gene F-box and WD-40 domain protein 28 Neighboring gene F-box and WD-40 domain protein 22

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC117492

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    F-box and WD-40 domain protein 14
    Names
    F-box only protein 12
    F-box protein 12

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001311159.1NP_001298088.1  F-box and WD-40 domain protein 14 isoform 2

      See identical proteins and their annotated locations for NP_001298088.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region compared to variant 1. It encodes isoform 2, which is shorter than isoform 1.
      Source sequence(s)
      AC122308, AK087709, AK166611, CT025696
      Consensus CDS
      CCDS81079.1
      UniProtKB/TrEMBL
      Q4FZL9, Q8C2Y5
      Related
      ENSMUSP00000107672.4, OTTMUSP00000034244, ENSMUST00000112041.5, OTTMUST00000067906
      Conserved Domains (1) summary
      pfam12937
      Location:448
      F-box-like; F-box-like
    2. NM_015793.2NP_056608.1  F-box and WD-40 domain protein 14 isoform 1

      See identical proteins and their annotated locations for NP_056608.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC122308, CT025696
      Consensus CDS
      CCDS23550.1
      UniProtKB/TrEMBL
      Q8C2Y5
      Related
      ENSMUSP00000143404.1, OTTMUSP00000034243, ENSMUST00000198844.4, OTTMUST00000067905
      Conserved Domains (2) summary
      COG2319
      Location:99316
      WD40; WD40 repeat [General function prediction only]
      pfam12937
      Location:448
      F-box-like; F-box-like

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      109270975..109287729 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006512182.3XP_006512245.1  F-box and WD-40 domain protein 14 isoform X4

      Conserved Domains (2) summary
      COG2319
      Location:99316
      WD40; WD40 repeat [General function prediction only]
      pfam12937
      Location:448
      F-box-like; F-box-like
    2. XM_017313455.1XP_017168944.1  F-box and WD-40 domain protein 14 isoform X1

    3. XM_017313457.1XP_017168946.1  F-box and WD-40 domain protein 14 isoform X3

    4. XM_017313456.1XP_017168945.1  F-box and WD-40 domain protein 14 isoform X2

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