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    Zdhhc18 zinc finger, DHHC domain containing 18 [ Mus musculus (house mouse) ]

    Gene ID: 503610, updated on 23-Jun-2021

    Summary

    Official Symbol
    Zdhhc18provided by MGI
    Official Full Name
    zinc finger, DHHC domain containing 18provided by MGI
    Primary source
    MGI:MGI:3527792
    See related
    Ensembl:ENSMUSG00000037553
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DHHC-18
    Expression
    Broad expression in spleen adult (RPKM 53.1), thymus adult (RPKM 41.2) and 23 other tissues See more
    Orthologs
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    Genomic context

    See Zdhhc18 in Genome Data Viewer
    Location:
    4; 4 D2.3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (133331969..133360801, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (133604554..133633490, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (133162907..133189344, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 42324 Neighboring gene stratifin Neighboring gene predicted gene 13213 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class V

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables palmitoyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables palmitoyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-cysteine S-palmitoyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular protein localization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in peptidyl-L-cysteine S-palmitoylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in peptidyl-L-cysteine S-palmitoylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein palmitoylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    palmitoyltransferase ZDHHC18
    Names
    DHHC domain-containing cysteine-rich protein 18
    zinc finger DHHC domain-containing protein 18
    NP_001017968.2
    XP_006539081.1
    XP_006539083.1
    XP_006539084.1
    XP_006539085.1
    XP_011248601.1
    XP_017175794.1
    XP_036020116.1
    XP_036020117.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017968.2NP_001017968.2  palmitoyltransferase ZDHHC18

      See identical proteins and their annotated locations for NP_001017968.2

      Status: VALIDATED

      Source sequence(s)
      AL627228, AY668950, BX537327, CJ049628
      Consensus CDS
      CCDS38906.1
      UniProtKB/Swiss-Prot
      Q5Y5T2
      Related
      ENSMUSP00000081260.5, ENSMUST00000084238.5
      Conserved Domains (1) summary
      pfam01529
      Location:183306
      zf-DHHC; DHHC palmitoyltransferase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      133331969..133360801 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017320305.3XP_017175794.1  palmitoyltransferase ZDHHC18 isoform X3

      Conserved Domains (1) summary
      pfam01529
      Location:183306
      DHHC; DHHC palmitoyltransferase
    2. XM_006539018.2XP_006539081.1  palmitoyltransferase ZDHHC18 isoform X1

      Conserved Domains (1) summary
      pfam01529
      Location:183306
      DHHC; DHHC palmitoyltransferase
    3. XM_011250299.3XP_011248601.1  palmitoyltransferase ZDHHC18 isoform X5

      See identical proteins and their annotated locations for XP_011248601.1

      Conserved Domains (1) summary
      pfam01529
      Location:183306
      DHHC; DHHC palmitoyltransferase
    4. XM_036164223.1XP_036020116.1  palmitoyltransferase ZDHHC18 isoform X2

      Conserved Domains (1) summary
      pfam01529
      Location:183268
      DHHC; DHHC palmitoyltransferase
    5. XM_036164224.1XP_036020117.1  palmitoyltransferase ZDHHC18 isoform X6

      Conserved Domains (1) summary
      cl19890
      Location:100265
      DHHC; DHHC palmitoyltransferase
    6. XM_006539022.3XP_006539085.1  palmitoyltransferase ZDHHC18 isoform X5

      See identical proteins and their annotated locations for XP_006539085.1

      Conserved Domains (1) summary
      pfam01529
      Location:183306
      DHHC; DHHC palmitoyltransferase
    7. XM_006539021.3XP_006539084.1  palmitoyltransferase ZDHHC18 isoform X4

      See identical proteins and their annotated locations for XP_006539084.1

      Conserved Domains (1) summary
      pfam01529
      Location:183306
      DHHC; DHHC palmitoyltransferase
    8. XM_006539020.3XP_006539083.1  palmitoyltransferase ZDHHC18 isoform X4

      See identical proteins and their annotated locations for XP_006539083.1

      Conserved Domains (1) summary
      pfam01529
      Location:183306
      DHHC; DHHC palmitoyltransferase

    RNA

    1. XR_390767.4 RNA Sequence

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