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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_008856.1 RefSeqGene
- Range
-
5045..37010
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001364440.2 → NP_001351369.1 methionine synthase reductase
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) represents the longest transcript. Variants 1, 2, 6, 7, and 8 all encode the same protein.
- Source sequence(s)
-
AC010346, AC025174
- UniProtKB/Swiss-Prot
-
Q7Z4M8
- Conserved Domains (2) summary
-
- cd06203
Location:277 → 697
- methionine_synthase_red; Human methionine synthase reductase (MSR) restores methionine sythase which is responsible for the regeneration of methionine from homocysteine, as well as the coversion of methyltetrahydrofolate to tetrahydrofolate. In MSR, electrons are transferred ...
- pfam00258
Location:6 → 142
- Flavodoxin_1; Flavodoxin
-
NM_001364441.2 → NP_001351370.1 methionine synthase reductase
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 6. Variants 1, 2, 6, 7, and 8 all encode the same protein.
- Source sequence(s)
-
AC010346, AC025174
- UniProtKB/Swiss-Prot
-
Q7Z4M8
- Conserved Domains (2) summary
-
- cd06203
Location:277 → 697
- methionine_synthase_red; Human methionine synthase reductase (MSR) restores methionine sythase which is responsible for the regeneration of methionine from homocysteine, as well as the coversion of methyltetrahydrofolate to tetrahydrofolate. In MSR, electrons are transferred ...
- pfam00258
Location:6 → 142
- Flavodoxin_1; Flavodoxin
-
NM_001364442.2 → NP_001351371.1 methionine synthase reductase
Status: REVIEWED
- Description
- Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 6. Variants 1, 2, 6, 7, and 8 all encode the same protein.
- Source sequence(s)
-
AC010346, AC025174
- UniProtKB/Swiss-Prot
-
Q7Z4M8
- Conserved Domains (2) summary
-
- cd06203
Location:277 → 697
- methionine_synthase_red; Human methionine synthase reductase (MSR) restores methionine sythase which is responsible for the regeneration of methionine from homocysteine, as well as the coversion of methyltetrahydrofolate to tetrahydrofolate. In MSR, electrons are transferred ...
- pfam00258
Location:6 → 142
- Flavodoxin_1; Flavodoxin
-
NM_002454.3 → NP_002445.2 methionine synthase reductase
See identical proteins and their annotated locations for NP_002445.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 6. Variants 1, 2, 6, 7, and 8 all encode the same protein.
- Source sequence(s)
-
BC054816, BC109216
- Consensus CDS
-
CCDS47190.1
- UniProtKB/Swiss-Prot
- Q7Z4M8, Q9UBK8
- Related
- ENSP00000402510.2, ENST00000440940.7
- Conserved Domains (2) summary
-
- cd06203
Location:277 → 697
- methionine_synthase_red; Human methionine synthase reductase (MSR) restores methionine sythase which is responsible for the regeneration of methionine from homocysteine, as well as the coversion of methyltetrahydrofolate to tetrahydrofolate. In MSR, electrons are transferred ...
- pfam00258
Location:6 → 142
- Flavodoxin_1; Flavodoxin
-
NM_024010.4 → NP_076915.3 methionine synthase reductase
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 6. Variants 1, 2, 6, 7, and 8 all encode the same protein.
- Source sequence(s)
-
AC010346, AC025174
- UniProtKB/Swiss-Prot
-
Q7Z4M8
- Related
- ENSP00000264668.2, ENST00000264668.6
- Conserved Domains (2) summary
-
- cd06203
Location:277 → 697
- methionine_synthase_red; Human methionine synthase reductase (MSR) restores methionine sythase which is responsible for the regeneration of methionine from homocysteine, as well as the coversion of methyltetrahydrofolate to tetrahydrofolate. In MSR, electrons are transferred ...
- pfam00258
Location:6 → 142
- Flavodoxin_1; Flavodoxin
RNA
-
NR_134480.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses an alternate splice site in an internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
BC054816, BC109217, DA384356
-
NR_134481.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AF121214, BC035977, BC054816
-
NR_134482.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks an internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
BC054816, BC062577, BC109217
-
NR_157168.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC010346, AC025174
-
NR_157169.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC010346, AC025174
- Related
-
ENST00000511461.5
-
NR_157170.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC010346, AC025174
-
NR_157171.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC010346, AC025174
-
NR_157172.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC010346, AC025174
-
NR_157173.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC010346, AC025174
-
NR_157174.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC010346, AC025174
-
NR_157175.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC010346, AC025174
-
NR_157176.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC010346, AC025174
-
NR_157177.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC010346, AC025174
-
NR_157178.2 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC010346, AC025174