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    MT-ND6 mitochondrially encoded NADH dehydrogenase 6 [ Homo sapiens (human) ]

    Gene ID: 4541, updated on 24-Jul-2021

    Summary

    Official Symbol
    MT-ND6provided by HGNC
    Official Full Name
    mitochondrially encoded NADH dehydrogenase 6provided by HGNC
    Primary source
    HGNC:HGNC:7462
    See related
    MIM:516006
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MTND6; ND6
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    Genomic context

    See MT-ND6 in Genome Data Viewer
    Annotation release Status Assembly Chr Location
    109.20210514 current GRCh38.p13 (GCF_000001405.39) MT (non-nuclear) NC_012920.1 (14149..14673, complement)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) MT (non-nuclear) NC_012920.1 (14149..14673, complement)

    Chromosome MT - NC_012920.1Genomic Context describing neighboring genes Neighboring gene tRNA Neighboring gene NADH dehydrogenase subunit 5 Neighboring gene tRNA Neighboring gene cytochrome b

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables NADH dehydrogenase (ubiquinone) activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, NADH to ubiquinone IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in mitochondrial respiratory chain complex I assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in response to cocaine IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to hydrogen peroxide IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to nicotine IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in mitochondrial inner membrane TAS
    Traceable Author Statement
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in respirasome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    NADH dehydrogenase subunit 6

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_012920.1 Reference assembly

      Range
      14149..14673 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_003024037.1 NADH dehydrogenase subunit 6 (mitochondrion) [Homo sapiens]

      See identical proteins and their annotated locations for YP_003024037.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P03923
      UniProtKB/TrEMBL
      U5Z977
      Related
      ENSP00000354665.2
      Conserved Domains (1) summary
      MTH00109
      Location:1174
      ND6; NADH dehydrogenase subunit 6; Provisional
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