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    TMEM151B transmembrane protein 151B [ Homo sapiens (human) ]

    Gene ID: 441151, updated on 17-Jun-2024

    Summary

    Official Symbol
    TMEM151Bprovided by HGNC
    Official Full Name
    transmembrane protein 151Bprovided by HGNC
    Primary source
    HGNC:HGNC:21315
    See related
    Ensembl:ENSG00000178233 AllianceGenome:HGNC:21315
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    TMEM193; C6orf137; bA444E17.5
    Summary
    Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in brain (RPKM 16.7), adrenal (RPKM 1.9) and 1 other tissue See more
    Orthologs
    NEW
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    Genomic context

    See TMEM151B in Genome Data Viewer
    Location:
    6p21.1
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (44270450..44279444)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (44104587..44113575)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (44238187..44247181)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene RNA polymerase I and III subunit C Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:44222709-44223424 Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:44224854-44225567 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24633 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24634 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24635 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24636 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24637 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:44232415-44232914 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:44243146-44243938 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17263 Neighboring gene uncharacterized LOC124901322 Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:44280829-44281388 Neighboring gene solute carrier family 35 member B2 Neighboring gene microRNA 4647 Neighboring gene NFKB inhibitor epsilon Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_91950 Neighboring gene t-complex-associated-testis-expressed 1 Neighboring gene alanyl-tRNA synthetase 2, mitochondrial Neighboring gene spermatogenesis associated serine rich 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Potential readthrough

    Included gene: SPATS1

    Clone Names

    • FLJ37046, FLJ42511, FLJ44683, FLJ44891

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    transmembrane protein 151B
    Names
    transmembrane protein 193

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001137560.2NP_001131032.1  transmembrane protein 151B

      See identical proteins and their annotated locations for NP_001131032.1

      Status: VALIDATED

      Source sequence(s)
      AL139392, AL353588, BC040881, BE671218, BM664874
      Consensus CDS
      CCDS47437.1
      UniProtKB/Swiss-Prot
      Q5T9V7, Q8IW70
      Related
      ENSP00000393161.2, ENST00000451188.7
      Conserved Domains (1) summary
      pfam14857
      Location:47492
      TMEM151; TMEM151 family

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      44270450..44279444
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      44104587..44113575
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001039704.1: Suppressed sequence

      Description
      NM_001039704.1: This RefSeq was permanently suppressed because currently there is insufficient data to support the transcript and the protein.