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    Dnaaf5 dynein, axonemal assembly factor 5 [ Mus musculus (house mouse) ]

    Gene ID: 433956, updated on 23-Jun-2021

    Summary

    Official Symbol
    Dnaaf5provided by MGI
    Official Full Name
    dynein, axonemal assembly factor 5provided by MGI
    Primary source
    MGI:MGI:3616079
    See related
    Ensembl:ENSMUSG00000025857
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Heat; C76907; Heatr2; BC053401
    Expression
    Ubiquitous expression in adrenal adult (RPKM 20.8), ovary adult (RPKM 20.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Dnaaf5 in Genome Data Viewer
    Location:
    5; 5 G2
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (139135888..139172265)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (139150133..139186510)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (139626177..139662459)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38726 Neighboring gene platelet derived growth factor, alpha Neighboring gene protein kinase, cAMP dependent regulatory, type I beta Neighboring gene Sad1 and UNC84 domain containing 1 Neighboring gene golgi to ER traffic protein 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC60818

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables dynein intermediate chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables dynein intermediate chain binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell projection organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cilium movement IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in cilium movement ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in inner dynein arm assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in inner dynein arm assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in outer dynein arm assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in outer dynein arm assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    NOT located_in motile cilium IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    dynein axonemal assembly factor 5
    Names
    HEAT repeat-containing protein 2
    dynein assembly factor 5, axonemal

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081265.2NP_001074734.1  dynein axonemal assembly factor 5 isoform 1

      See identical proteins and their annotated locations for NP_001074734.1

      Status: VALIDATED

      Source sequence(s)
      AC125065
      Consensus CDS
      CCDS39349.1
      UniProtKB/Swiss-Prot
      B9EJR8
      Related
      ENSMUSP00000026975.7, ENSMUST00000026975.11
      Conserved Domains (2) summary
      pfam13830
      Location:41198
      DUF4192; Domain of unknown function (DUF4192)
      sd00044
      Location:165193
      HEAT; HEAT repeat [structural motif]
    2. NM_001363485.1NP_001350414.1  dynein axonemal assembly factor 5 isoform 2

      Status: VALIDATED

      Source sequence(s)
      BC158066, BG228650, CK627764
      Consensus CDS
      CCDS90005.1
      Related
      ENSMUSP00000142924.2, ENSMUST00000196441.2
      Conserved Domains (1) summary
      sd00044
      Location:405433
      HEAT; HEAT repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      139135888..139172265
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_003955669.1 RNA Sequence

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