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    Pusl1 pseudouridylate synthase-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 433813, updated on 23-Jun-2021

    Summary

    Official Symbol
    Pusl1provided by MGI
    Official Full Name
    pseudouridylate synthase-like 1provided by MGI
    Primary source
    MGI:MGI:3047787
    See related
    Ensembl:ENSMUSG00000051557
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D18346; AI853843; 2810021I11Rik
    Expression
    Ubiquitous expression in ovary adult (RPKM 20.1), adrenal adult (RPKM 18.8) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Pusl1 in Genome Data Viewer
    Location:
    4 E2; 4 87.66 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (155973314..155976231, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (155888857..155891858, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (155262966..155265871, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene dishevelled segment polarity protein 1 Neighboring gene taste receptor, type 1, member 3 Neighboring gene ceramide-1-phosphate transfer protein Neighboring gene integrator complex subunit 11 Neighboring gene ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 Neighboring gene sodium channel, nonvoltage-gated 1, delta

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables pseudouridine synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in RNA modification IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in pseudouridine synthesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within tRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA pseudouridine synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    tRNA pseudouridine synthase-like 1
    Names
    tRNA pseudouridylate synthase-like 1
    tRNA-uridine isomerase-like 1
    NP_001028662.1
    XP_030109505.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033490.1NP_001028662.1  tRNA pseudouridine synthase-like 1

      See identical proteins and their annotated locations for NP_001028662.1

      Status: VALIDATED

      Source sequence(s)
      AL670236
      Consensus CDS
      CCDS51404.1
      UniProtKB/Swiss-Prot
      A2ADA5
      Related
      ENSMUSP00000095344.5, ENSMUST00000097737.5
      Conserved Domains (2) summary
      cd02570
      Location:18284
      PseudoU_synth_EcTruA; Eukaryotic and bacterial pseudouridine synthases similar to E. coli TruA
      PRK00021
      Location:13284
      truA; tRNA pseudouridine synthase A; Validated

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      155973314..155976231 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030253645.2XP_030109505.1  tRNA pseudouridine synthase-like 1 isoform X1

      Conserved Domains (1) summary
      cd02570
      Location:10249
      PseudoU_synth_EcTruA; Eukaryotic and bacterial pseudouridine synthases similar to E. coli TruA

    RNA

    1. XR_390764.4 RNA Sequence

    2. XR_001784162.3 RNA Sequence

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