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    bam bag of marbles [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43038, updated on 4-Jul-2024

    Summary

    Official Symbol
    bamprovided by FlyBase
    Official Full Name
    bag of marblesprovided by FlyBase
    Primary source
    FLYBASE:FBgn0000158
    Locus tag
    Dmel_CG10422
    See related
    AllianceGenome:FB:FBgn0000158
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    alpha; Bam; BAM; Bam-C; BamC; BamF; CG10422; Dmel\CG10422; fs(3)neo61; ham
    Summary
    Enables mRNA 3'-UTR binding activity; translation repressor activity, mRNA regulatory element binding; and ubiquitin binding activity. Involved in several processes, including gamete generation; regulation of cellular protein metabolic process; and regulation of signal transduction. Located in fusome and spectrosome. Is expressed in cystoblast and gonad. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
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    Genomic context

    See bam in Genome Data Viewer
    Location:
    96C7-96C8; 3-87 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25243039..25245109, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21068761..21070779, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Juvenile hormone binding protein 7 Neighboring gene takeout Neighboring gene uncharacterized protein Neighboring gene stable intronic sequence RNA CR46364 Neighboring gene Ribosomal protein S27 Neighboring gene Nucleoporin 37kD

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables mRNA 3'-UTR binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables mRNA regulatory element binding translation repressor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables ubiquitin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell competition in a multicellular organism IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cystoblast division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in female germ-line stem cell asymmetric division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in fusome organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in gamete generation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in germ-line stem cell division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in germ-line stem cell population maintenance IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in germ-line stem cell population maintenance IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in germ-line stem cell population maintenance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in germarium-derived female germ-line cyst formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in male germline stem cell symmetric division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of peptidoglycan recognition protein signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of translation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in oogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of protein K63-linked deubiquitination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of protein deubiquitination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of smoothened signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of stem cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in spermatogonial cell division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in fusome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in spectrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    bag of marbles
    Names
    CG10422-PA
    bag of marble
    bag-of-marbles
    bam-PA
    transcript alpha

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25243039..25245109 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057452.4NP_476800.1  bag of marbles [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476800.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P22745, Q2PNQ8, Q2PNQ9, Q2PNR5, Q2PNR8, Q2PNR9, Q2PNS3, Q2PNS6, Q2PNS8, Q2PNT1, Q8MRX8, Q9VBV0
      UniProtKB/TrEMBL
      A1YJS5, B5RIV8
      Related
      FBpp0084243