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    eff effete [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41785, updated on 8-Oct-2018

    Summary

    Official Symbol
    effprovided by FlyBase
    Official Full Name
    effeteprovided by FlyBase
    Primary source
    FLYBASE:FBgn0011217
    Locus tag
    Dmel_CG7425
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    3527; 6535; anon-WO0118547.343; CG7425; Dmel\CG7425; E(Pc)88D; Eff; EFF; fs(3)01295; l(3)01462; l(3)j2C8; l(3)s1782; mei68; ms(3)01295; ms(3)1; ms(3)3; ms(3)88D; ms(3)neo2; ms(3)ry1; ms(3)ry3; SS3-3; Ubc-D1; UBC4; Ubc5; UbcD; UBCD-1; ubcD1; UbcD1; UBCD1; UbcH5

    Genomic context

    See eff in Genome Data Viewer
    Location:
    88D2-88D2; 3-56 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14732414..14741319, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (10558136..10567041, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene kibra Neighboring gene uncharacterized protein Neighboring gene javelin-like Neighboring gene Senescence marker protein-30 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    ubiquitin conjugating enzyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ubiquitin conjugating enzyme activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ubiquitin conjugating enzyme activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    ubiquitin protein ligase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ubiquitin protein ligase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ubiquitin protein ligase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    anaphase-promoting complex-dependent catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    chromosome organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    compound eye morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    compound eye photoreceptor cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    female germ-line stem cell asymmetric division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    germ-line stem cell population maintenance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    male meiotic nuclear division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neuron remodeling IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein linear polyubiquitination IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein polyubiquitination IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein polyubiquitination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein ubiquitination IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    regulation of R7 cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of protein stability IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ubiquitin-dependent protein catabolic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    ubiquitin-dependent protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    effete
    Names
    CG7425-PA
    CG7425-PB
    CG7425-PC
    eff-PA
    eff-PB
    eff-PC
    effette
    meiotic 68
    suppressor of GMR-sina 3-3
    ubiquitin conjugating enzyme 1

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      14732414..14741319 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275650.1NP_001262579.1  effete, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262579.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P25867
      UniProtKB/TrEMBL
      A0A0B4KHJ1
      Related
      FBpp0307824, FBtr0336876
      Conserved Domains (1) summary
      cl00154
      Location:1146
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    2. NM_169601.2NP_731941.1  effete, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731941.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P25867
      UniProtKB/TrEMBL
      A0A0B4KHJ1
      Related
      FBpp0082477, FBtr0083018
      Conserved Domains (1) summary
      cl00154
      Location:1146
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    3. NM_001275649.1NP_001262578.1  effete, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262578.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P25867
      UniProtKB/TrEMBL
      A0A0B4KHJ1
      Related
      FBpp0302691, FBtr0310554
      Conserved Domains (1) summary
      cl00154
      Location:1146
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
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