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    FN1 fibronectin 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 403845, updated on 6-Oct-2018

    Summary

    Official Symbol
    FN1provided by VGNC
    Official Full Name
    fibronectin 1provided by VGNC
    Primary source
    VGNC:VGNC:57383
    See related
    Ensembl:ENSCAFG00000014345
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    FN
    Orthologs

    Genomic context

    See FN1 in Genome Data Viewer
    Location:
    chromosome: 37
    Exon count:
    45
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 37 NC_006619.3 (22456854..22522410, complement)

    Chromosome 37 - NC_006619.3Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily A member 12 Neighboring gene 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase Neighboring gene uncharacterized LOC106558322 Neighboring gene uncharacterized LOC111094355

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006619.3 Chromosome 37 Reference CanFam3.1 Primary Assembly

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    heparin binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acute-phase response IEA
    Inferred from Electronic Annotation
    more info
     
    cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of cell shape IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006619.3 Reference CanFam3.1 Primary Assembly

      Range
      22456854..22522410 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014110987.1XP_013966462.1  fibronectin isoform X11

      Conserved Domains (6) summary
      smart00059
      Location:339387
      FN2; Fibronectin type 2 domain
      smart00058
      Location:172216
      FN1; Fibronectin type 1 domain
      cd00061
      Location:20702109
      FN1; Fibronectin type 1 domain, approximately 40 residue long with two conserved disulfide bridges. FN1 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces ...
      cd00063
      Location:18001880
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00039
      Location:217256
      fn1; Fibronectin type I domain
      pfam00041
      Location:14351516
      fn3; Fibronectin type III domain
    2. XM_014110984.1XP_013966459.1  fibronectin isoform X9

      UniProtKB/TrEMBL
      J9P8M2
      Related
      ENSCAFP00000042101.1, ENSCAFT00000043476.2
      Conserved Domains (6) summary
      smart00059
      Location:339387
      FN2; Fibronectin type 2 domain
      smart00058
      Location:172216
      FN1; Fibronectin type 1 domain
      cd00061
      Location:21652204
      FN1; Fibronectin type 1 domain, approximately 40 residue long with two conserved disulfide bridges. FN1 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces ...
      cd00063
      Location:18001880
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00039
      Location:217256
      fn1; Fibronectin type I domain
      pfam00041
      Location:14351516
      fn3; Fibronectin type III domain
    3. XM_014110983.1XP_013966458.1  fibronectin isoform X7

      Conserved Domains (6) summary
      smart00059
      Location:339387
      FN2; Fibronectin type 2 domain
      smart00058
      Location:172216
      FN1; Fibronectin type 1 domain
      cd00061
      Location:21902229
      FN1; Fibronectin type 1 domain, approximately 40 residue long with two conserved disulfide bridges. FN1 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces ...
      cd00063
      Location:18001880
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00039
      Location:217256
      fn1; Fibronectin type I domain
      pfam00041
      Location:14351516
      fn3; Fibronectin type III domain
    4. XM_014110982.1XP_013966457.1  fibronectin isoform X5

      Conserved Domains (6) summary
      smart00059
      Location:339387
      FN2; Fibronectin type 2 domain
      smart00058
      Location:172216
      FN1; Fibronectin type 1 domain
      cd00061
      Location:22552294
      FN1; Fibronectin type 1 domain, approximately 40 residue long with two conserved disulfide bridges. FN1 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces ...
      cd00063
      Location:18901970
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00039
      Location:217256
      fn1; Fibronectin type I domain
      pfam00041
      Location:14351516
      fn3; Fibronectin type III domain
    5. XM_014110981.1XP_013966456.1  fibronectin isoform X4

      Conserved Domains (6) summary
      smart00059
      Location:339387
      FN2; Fibronectin type 2 domain
      smart00058
      Location:172216
      FN1; Fibronectin type 1 domain
      cd00061
      Location:22802319
      FN1; Fibronectin type 1 domain, approximately 40 residue long with two conserved disulfide bridges. FN1 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces ...
      cd00063
      Location:18901970
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00039
      Location:217256
      fn1; Fibronectin type I domain
      pfam00041
      Location:14351516
      fn3; Fibronectin type III domain
    6. XM_014110989.1XP_013966464.1  fibronectin isoform X10

      Conserved Domains (6) summary
      smart00059
      Location:339387
      FN2; Fibronectin type 2 domain
      smart00058
      Location:172216
      FN1; Fibronectin type 1 domain
      cd00061
      Location:21612200
      FN1; Fibronectin type 1 domain, approximately 40 residue long with two conserved disulfide bridges. FN1 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces ...
      cd00063
      Location:18911971
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00039
      Location:217256
      fn1; Fibronectin type I domain
      pfam00041
      Location:15261607
      fn3; Fibronectin type III domain
    7. XM_022415240.1XP_022270948.1  fibronectin isoform X3

      Conserved Domains (6) summary
      smart00059
      Location:339387
      FN2; Fibronectin type 2 domain
      smart00058
      Location:172216
      FN1; Fibronectin type 1 domain
      cd00061
      Location:22812320
      FN1; Fibronectin type 1 domain, approximately 40 residue long with two conserved disulfide bridges. FN1 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces ...
      cd00063
      Location:18911971
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00039
      Location:217256
      fn1; Fibronectin type I domain
      pfam00041
      Location:15261607
      fn3; Fibronectin type III domain
    8. XM_022415242.1XP_022270950.1  fibronectin isoform X8

      Conserved Domains (6) summary
      smart00059
      Location:339387
      FN2; Fibronectin type 2 domain
      smart00058
      Location:172216
      FN1; Fibronectin type 1 domain
      cd00061
      Location:21692208
      FN1; Fibronectin type 1 domain, approximately 40 residue long with two conserved disulfide bridges. FN1 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces ...
      cd00063
      Location:19812061
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00039
      Location:217256
      fn1; Fibronectin type I domain
      pfam00041
      Location:15261607
      fn3; Fibronectin type III domain
    9. XM_022415241.1XP_022270949.1  fibronectin isoform X6

      Conserved Domains (6) summary
      smart00059
      Location:339387
      FN2; Fibronectin type 2 domain
      smart00058
      Location:172216
      FN1; Fibronectin type 1 domain
      cd00061
      Location:22512290
      FN1; Fibronectin type 1 domain, approximately 40 residue long with two conserved disulfide bridges. FN1 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces ...
      cd00063
      Location:19812061
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00039
      Location:217256
      fn1; Fibronectin type I domain
      pfam00041
      Location:15261607
      fn3; Fibronectin type III domain
    10. XM_022415239.1XP_022270947.1  fibronectin isoform X2

      Conserved Domains (6) summary
      smart00059
      Location:339387
      FN2; Fibronectin type 2 domain
      smart00058
      Location:172216
      FN1; Fibronectin type 1 domain
      cd00061
      Location:23462385
      FN1; Fibronectin type 1 domain, approximately 40 residue long with two conserved disulfide bridges. FN1 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces ...
      cd00063
      Location:19812061
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00039
      Location:217256
      fn1; Fibronectin type I domain
      pfam00041
      Location:15261607
      fn3; Fibronectin type III domain
    11. XM_014110988.1XP_013966463.1  fibronectin isoform X1

      Related
      ENSCAFP00000021176.3, ENSCAFT00000022799.3
      Conserved Domains (6) summary
      smart00059
      Location:339387
      FN2; Fibronectin type 2 domain
      smart00058
      Location:172216
      FN1; Fibronectin type 1 domain
      cd00061
      Location:23712410
      FN1; Fibronectin type 1 domain, approximately 40 residue long with two conserved disulfide bridges. FN1 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces ...
      cd00063
      Location:19812061
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00039
      Location:217256
      fn1; Fibronectin type I domain
      pfam00041
      Location:15261607
      fn3; Fibronectin type III domain
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