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    OR14I1 olfactory receptor family 14 subfamily I member 1 [ Homo sapiens (human) ]

    Gene ID: 401994, updated on 13-Mar-2020

    Summary

    Official Symbol
    OR14I1provided by HGNC
    Official Full Name
    olfactory receptor family 14 subfamily I member 1provided by HGNC
    Primary source
    HGNC:HGNC:19575
    See related
    Ensembl:ENSG00000189181 MIM:618516
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    OR5BU1; OR5BU1P
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
    Expression
    Biased expression in brain (RPKM 1.0) and testis (RPKM 0.1) See more
    Orthologs

    Genomic context

    See OR14I1 in Genome Data Viewer
    Location:
    1q44
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    109.20200228 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (248681296..248685566, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (248844580..248862258, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily T member 10 Neighboring gene olfactory receptor family 2 subfamily T member 35 Neighboring gene olfactory receptor family 2 subfamily T member 27 Neighboring gene LY6/PLAUR domain containing 9, pseudogene Neighboring gene adenosylhomocysteinase pseudogene 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    odorant binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
     
    sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    olfactory receptor 14I1
    Names
    olfactory receptor 5BU1
    olfactory receptor, family 5, subfamily BU, member 1 pseudogene

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004734.1NP_001004734.1  olfactory receptor 14I1

      See identical proteins and their annotated locations for NP_001004734.1

      Status: PROVISIONAL

      Source sequence(s)
      AC098483
      Consensus CDS
      CCDS31125.1
      UniProtKB/Swiss-Prot
      A6ND48
      Related
      ENSP00000339726.3, ENST00000342623.5
      Conserved Domains (2) summary
      pfam00001
      Location:39288
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:29303
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

      Range
      248681296..248685566 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005273132.3XP_005273189.1  olfactory receptor 14I1 isoform X1

      See identical proteins and their annotated locations for XP_005273189.1

      UniProtKB/Swiss-Prot
      A6ND48
      Conserved Domains (2) summary
      pfam00001
      Location:39288
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:29303
      7tm_4; Olfactory receptor
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