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    GOLGA7B golgin A7 family member B [ Homo sapiens (human) ]

    Gene ID: 401647, updated on 5-Mar-2024

    Summary

    Official Symbol
    GOLGA7Bprovided by HGNC
    Official Full Name
    golgin A7 family member Bprovided by HGNC
    Primary source
    HGNC:HGNC:31668
    See related
    Ensembl:ENSG00000155265 MIM:614189; AllianceGenome:HGNC:31668
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C10orf132; C10orf133; bA459F3.4; bA451M19.3
    Summary
    Enables enzyme binding activity. Predicted to be involved in peptidyl-L-cysteine S-palmitoylation and protein targeting to membrane. Predicted to be located in Golgi membrane. Predicted to be part of palmitoyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in brain (RPKM 7.2), skin (RPKM 7.1) and 11 other tissues See more
    Orthologs
    NEW
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    Genomic context

    Location:
    10q24.2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (97849843..97871578)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (98729980..98751715)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (99609600..99631335)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 10024 Neighboring gene secreted frizzled related protein 5 Neighboring gene uncharacterized LOC107984260 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:99599631-99600830 Neighboring gene GOLGA7B divergent transcript Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:99601331-99602273 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:99635581-99636081 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr10:99641761-99642960 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:99647957-99648570 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:99648571-99649183 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:99649184-99649796 Neighboring gene cartilage acidic protein 1 Neighboring gene microRNA 3085 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:99674250-99674826 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:99712853-99713551 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:99734318-99734920 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:99734921-99735522 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3860 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr10:99885542-99886741 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:99894841-99895630 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3862 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:99911422-99912174 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:99912926-99913677 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:99913678-99914428 Neighboring gene R3H domain and coiled-coil containing 1 like Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3863 Neighboring gene NANOG hESC enhancer GRCh37_chr10:99933024-99933525 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:99983165-99983698 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:99983699-99984230

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Phenotypes

    EBI GWAS Catalog

    Description
    Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia.
    EBI GWAS Catalog

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ43465, MGC131701

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables enzyme binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in peptidyl-L-cysteine S-palmitoylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of palmitoyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    golgin subfamily A member 7B
    Names
    golgi autoantigen, golgin subfamily a, 7B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001010917.3NP_001010917.1  golgin subfamily A member 7B

      See identical proteins and their annotated locations for NP_001010917.1

      Status: VALIDATED

      Source sequence(s)
      AK125454, AL358938, AW172573, BC008047, BC110810, BI754792, BM713854, BQ950672, CA308047, DN831741
      Consensus CDS
      CCDS31265.1
      UniProtKB/Swiss-Prot
      Q2TAP0, Q5T4F5
      Related
      ENSP00000359634.1, ENST00000370602.6
      Conserved Domains (1) summary
      pfam10256
      Location:21133
      Erf4; Golgin subfamily A member 7/ERF4 family

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      97849843..97871578
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      98729980..98751715
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)