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    OR11H4 olfactory receptor family 11 subfamily H member 4 [ Homo sapiens (human) ]

    Gene ID: 390442, updated on 17-Jun-2024

    Summary

    Official Symbol
    OR11H4provided by HGNC
    Official Full Name
    olfactory receptor family 11 subfamily H member 4provided by HGNC
    Primary source
    HGNC:HGNC:15347
    See related
    Ensembl:ENSG00000176198 AllianceGenome:HGNC:15347
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    OR14-36
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
    Orthologs
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    Genomic context

    See OR11H4 in Genome Data Viewer
    Location:
    14q11.2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (20239286..20244349)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (14436092..14441147)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (20707445..20712508)

    Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 11 subfamily H member 6 Neighboring gene olfactory receptor family 11 subfamily H member 7 (gene/pseudogene) Neighboring gene uncharacterized LOC124903279 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr14:20763215-20764414 Neighboring gene tetratricopeptide repeat domain 5 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8067

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General protein information

    Preferred Names
    olfactory receptor 11H4
    Names
    olfactory receptor OR14-36

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004479.2NP_001004479.2  olfactory receptor 11H4

      Status: VALIDATED

      Source sequence(s)
      AL356019
      Consensus CDS
      CCDS32034.2
      UniProtKB/Swiss-Prot
      B2RNQ4, Q6IF07, Q8NGC9
      UniProtKB/TrEMBL
      A0A126GW19, A0A286YFI7
      Related
      ENSP00000493183.1, ENST00000641082.1
      Conserved Domains (1) summary
      cd15913
      Location:25294
      7tmA_OR11G-like; olfactory receptor OR11G and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

      Range
      20239286..20244349
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_025791796.1 Reference GRCh38.p14 PATCHES

      Range
      441967..447030
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060938.1 Alternate T2T-CHM13v2.0

      Range
      14436092..14441147
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)