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    CG5021 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39025, updated on 11-Apr-2024

    Summary

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    Official Symbol
    CG5021provided by FlyBase
    Primary source
    FLYBASE:FBgn0035944
    Locus tag
    Dmel_CG5021
    See related
    AllianceGenome:FB:FBgn0035944
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5021
    Summary
    Predicted to be involved in protein secretion and vesicle-mediated transport. Predicted to be integral component of Golgi membrane. Is expressed in several structures, including anterior endoderm anlage; embryonic/larval digestive system; germ layer; hindgut proper primordium; and presumptive embryonic/larval digestive system. Orthologous to several human genes including TVP23A (trans-golgi network vesicle protein 23 homolog A) and TVP23B (trans-golgi network vesicle protein 23 homolog B). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See CG5021 in Genome Data Viewer
    Location:
    66E5-66E5; 3-27 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (8966829..8968171)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (8959929..8961271)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Valyl-tRNA synthetase, mitochondrial Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene pixie

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity. Fox RM, et al. J Cell Biol, 2010 Nov 1. PMID 21041443, Free PMC Article
    2. Identification of Drosophila centromere associated proteins by quantitative affinity purification-mass spectrometry. Barth TK, et al. Data Brief, 2015 Sep. PMID 26306323, Free PMC Article
    3. Endogenously imprinted genes in Drosophila melanogaster. McEachern LA, et al. Mol Genet Genomics, 2014 Aug. PMID 24658702
    4. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    5. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein secretion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5021-PA
    CG5021-PB
    CG5021-PC
    CG5021-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      8966829..8968171
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001169919.2 → NP_001163390.1  uncharacterized protein Dmel_CG5021, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163390.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IQC1, Q8SYV2, Q9VSR9
      UniProtKB/TrEMBL
      E1JI84, E4NKP0
      Conserved Domains (1) summary
      pfam05832
      Location:37 → 177
      DUF846; Eukaryotic protein of unknown function (DUF846)

    2. NM_001169920.2 → NP_001163391.1  uncharacterized protein Dmel_CG5021, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163391.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JI85, E4NKP0
      Conserved Domains (1) summary
      pfam05832
      Location:34 → 174
      DUF846; Eukaryotic protein of unknown function (DUF846)

    3. NM_168304.2 → NP_729433.1  uncharacterized protein Dmel_CG5021, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729433.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E4NKP0, H0RND2
      Related
      FBpp0076241
      Conserved Domains (1) summary
      pfam05832
      Location:34 → 169
      DUF846; Eukaryotic protein of unknown function (DUF846)

    4. NM_140013.3 → NP_648270.2  uncharacterized protein Dmel_CG5021, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648270.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      E4NKP0
      Related
      FBpp0076240
      Conserved Domains (1) summary
      pfam05832
      Location:37 → 172
      DUF846; Eukaryotic protein of unknown function (DUF846)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E1JI84 E1JI84
    E1JI85 E1JI85
    Q8IQC1.2 Q8IQC1

    Gene LinkOut

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