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    SFTA2 surfactant associated 2 [ Homo sapiens (human) ]

    Gene ID: 389376, updated on 17-Jun-2024

    Summary

    Official Symbol
    SFTA2provided by HGNC
    Official Full Name
    surfactant associated 2provided by HGNC
    Primary source
    HGNC:HGNC:18386
    See related
    Ensembl:ENSG00000196260 AllianceGenome:HGNC:18386
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    SP-G; SFTPG; UNQ541; GSGL541
    Summary
    Predicted to be located in Golgi apparatus; extracellular region; and transport vesicle. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward lung (RPKM 71.0) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See SFTA2 in Genome Data Viewer
    Location:
    6p21.33
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (30931353..30932170, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (30796017..30796834, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (30899130..30899947, complement)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene general transcription factor IIH subunit 4 Neighboring gene valyl-tRNA synthetase 2, mitochondrial Neighboring gene MED14-independent group 3 enhancer GRCh37_chr6:30889690-30890889 Neighboring gene uncharacterized LOC124901299 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:30905665-30906166 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:30908586-30909423 Neighboring gene mucin like 3 Neighboring gene HLA complex group 21

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    surfactant-associated protein 2
    Names
    surfactant associated protein G

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205854.3NP_995326.1  surfactant-associated protein 2 precursor

      See identical proteins and their annotated locations for NP_995326.1

      Status: VALIDATED

      Source sequence(s)
      AI857998, AY359057, BC039677, T94049
      Consensus CDS
      CCDS4691.1
      UniProtKB/Swiss-Prot
      A2ABK7, A2ACH1, B7ZCJ7, Q6UW10
      UniProtKB/TrEMBL
      A0A140T9P5, A0A1U9X8K0
      Related
      ENSP00000351989.3, ENST00000359086.4
      Conserved Domains (1) summary
      pfam15210
      Location:2078
      SFTA2; Surfactant-associated protein 2

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      30931353..30932170 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_2

    Genomic

    1. NT_113891.3 Reference GRCh38.p14 ALT_REF_LOCI_2

      Range
      2410947..2411764 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_3

    Genomic

    1. NT_167245.2 Reference GRCh38.p14 ALT_REF_LOCI_3

      Range
      2187655..2188472 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_4

    Genomic

    1. NT_167246.2 Reference GRCh38.p14 ALT_REF_LOCI_4

      Range
      2241591..2242408 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_5

    Genomic

    1. NT_167247.2 Reference GRCh38.p14 ALT_REF_LOCI_5

      Range
      2275484..2276301 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCh38.p14 ALT_REF_LOCI_6

    Genomic

    1. NT_167248.2 Reference GRCh38.p14 ALT_REF_LOCI_6

      Range
      2186505..2187322 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      30796017..30796834 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)