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    SKIDA1 SKI/DACH domain containing 1 [ Homo sapiens (human) ]

    Gene ID: 387640, updated on 5-Mar-2024

    Summary

    Official Symbol
    SKIDA1provided by HGNC
    Official Full Name
    SKI/DACH domain containing 1provided by HGNC
    Primary source
    HGNC:HGNC:32697
    See related
    Ensembl:ENSG00000180592 AllianceGenome:HGNC:32697
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    DLN-1; C10orf140
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See SKIDA1 in Genome Data Viewer
    Location:
    10p12.31
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (21513475..21525682, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (21532596..21548235, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (21802404..21814611, complement)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124902598 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21783452-21784245 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2186 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2187 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2188 Neighboring gene MIR1915 host gene Neighboring gene ReSE screen-validated silencer GRCh37_chr10:21793394-21793626 Neighboring gene microRNA 1915 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2189 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21814003-21814646 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21814647-21815290 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2191 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2192 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:21816390-21816548 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr10:21817867-21818510 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21822730-21823443 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2196 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2197 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:21824159-21824871 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21825135-21825648 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:21840002-21840186 Neighboring gene MLLT10 histone lysine methyltransferase DOT1L cofactor Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21844418-21845000 Neighboring gene RNA, U6 small nuclear 306, pseudogene Neighboring gene solute carrier family 4 member 8 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    EBI GWAS Catalog

    Description
    GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
    EBI GWAS Catalog

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    SKI/DACH domain-containing protein 1
    Names
    protein DLN-1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207371.4NP_997254.3  SKI/DACH domain-containing protein 1

      See identical proteins and their annotated locations for NP_997254.3

      Status: VALIDATED

      Source sequence(s)
      AK131456, AL358780, AL834446, BI497298, DB320086
      Consensus CDS
      CCDS44363.1
      UniProtKB/Swiss-Prot
      B1ANA5, E9PAX1, F5H7M0, Q1XH10, Q6ZMX4, Q8N3C3
      Related
      ENSP00000410041.2, ENST00000449193.7
      Conserved Domains (2) summary
      pfam02437
      Location:1095
      Ski_Sno; SKI/SNO/DAC family
      pfam15223
      Location:475906
      DUF4584; Domain of unknown function (DUF4584)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      21513475..21525682 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047425204.1XP_047281160.1  SKI/DACH domain-containing protein 1 isoform X1

      UniProtKB/Swiss-Prot
      B1ANA5, E9PAX1, F5H7M0, Q1XH10, Q6ZMX4, Q8N3C3
    2. XM_047425205.1XP_047281161.1  SKI/DACH domain-containing protein 1 isoform X1

      UniProtKB/Swiss-Prot
      B1ANA5, E9PAX1, F5H7M0, Q1XH10, Q6ZMX4, Q8N3C3

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      21532596..21548235 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054365848.1XP_054221823.1  SKI/DACH domain-containing protein 1 isoform X2

    2. XM_054365851.1XP_054221826.1  SKI/DACH domain-containing protein 1 isoform X1

    3. XM_054365850.1XP_054221825.1  SKI/DACH domain-containing protein 1 isoform X1

    4. XM_054365849.1XP_054221824.1  SKI/DACH domain-containing protein 1 isoform X3

    5. XM_054365847.1XP_054221822.1  SKI/DACH domain-containing protein 1 isoform X2