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    Prdm10 PR domain containing 10 [ Mus musculus (house mouse) ]

    Gene ID: 382066, updated on 2-Oct-2018

    Summary

    Official Symbol
    Prdm10provided by MGI
    Official Full Name
    PR domain containing 10provided by MGI
    Primary source
    MGI:MGI:2682952
    See related
    Ensembl:ENSMUSG00000042496 Vega:OTTMUSG00000031586
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm1112; tristanin
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 3.0), CNS E14 (RPKM 3.0) and 28 other tissues See more
    Orthologs

    Genomic context

    See Prdm10 in Genome Data Viewer
    Location:
    9; 9 A4
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (31276104..31381731)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (31122692..31186128)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene amyloid beta (A4) precursor-like protein 2 Neighboring gene predicted gene, 33535 Neighboring gene predicted gene 7244 Neighboring gene predicted gene 10910 Neighboring gene nuclear factor related to kappa B binding protein Neighboring gene transmembrane protein 45b Neighboring gene U2 small nuclear ribonucleoprotein B pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

    Markers

    Homology

    Clone Names

    • MGC73898

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    methylation IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    colocalizes_with histone methyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    PR domain zinc finger protein 10
    Names
    PR domain-containing protein 10
    NP_001074286.1
    XP_006510527.1
    XP_006510528.1
    XP_006510529.1
    XP_006510530.1
    XP_006510531.1
    XP_006510532.1
    XP_006510533.1
    XP_006510534.1
    XP_011240870.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080817.1NP_001074286.1  PR domain zinc finger protein 10 precursor

      Status: PROVISIONAL

      Source sequence(s)
      AC167244
      Consensus CDS
      CCDS40570.1
      UniProtKB/TrEMBL
      D3YYD1
      Related
      ENSMUSP00000074104.3, ENSMUST00000074510.3
      Conserved Domains (4) summary
      sd00017
      Location:559579
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:585607
      zf-C2H2; Zinc finger, C2H2 type
      pfam00856
      Location:165270
      SET; SET domain
      pfam16638
      Location:350455
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      31276104..31381731
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011242568.2XP_011240870.1  PR domain zinc finger protein 10 isoform X7

      Conserved Domains (5) summary
      COG5048
      Location:553629
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:526546
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00856
      Location:214319
      SET; SET domain
      pfam12171
      Location:351370
      zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding
      pfam16638
      Location:399504
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
    2. XM_006510469.3XP_006510532.1  PR domain zinc finger protein 10 isoform X4

      Conserved Domains (4) summary
      sd00017
      Location:587607
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:613635
      zf-C2H2; Zinc finger, C2H2 type
      pfam00856
      Location:189294
      SET; SET domain
      pfam16638
      Location:374479
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
    3. XM_006510464.3XP_006510527.1  PR domain zinc finger protein 10 isoform X1

      See identical proteins and their annotated locations for XP_006510527.1

      Conserved Domains (4) summary
      sd00017
      Location:612632
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:638660
      zf-C2H2; Zinc finger, C2H2 type
      pfam00856
      Location:214319
      SET; SET domain
      pfam16638
      Location:399504
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
    4. XM_006510468.3XP_006510531.1  PR domain zinc finger protein 10 isoform X3

      Conserved Domains (4) summary
      sd00017
      Location:604624
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:630652
      zf-C2H2; Zinc finger, C2H2 type
      pfam00856
      Location:214319
      SET; SET domain
      pfam16638
      Location:399496
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
    5. XM_006510467.3XP_006510530.1  PR domain zinc finger protein 10 isoform X2

      Related
      ENSMUSP00000149526.1, OTTMUSP00000079297, ENSMUST00000215499.1, OTTMUST00000153137
      Conserved Domains (4) summary
      sd00017
      Location:608628
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:634656
      zf-C2H2; Zinc finger, C2H2 type
      pfam00856
      Location:214319
      SET; SET domain
      pfam16638
      Location:399504
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
    6. XM_006510470.3XP_006510533.1  PR domain zinc finger protein 10 isoform X5

      Conserved Domains (3) summary
      sd00017
      Location:544564
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:570592
      zf-C2H2; Zinc finger, C2H2 type
      pfam16638
      Location:331436
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
    7. XM_006510471.3XP_006510534.1  PR domain zinc finger protein 10 isoform X6

      Conserved Domains (5) summary
      sd00017
      Location:520540
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:518540
      zf-C2H2; Zinc finger, C2H2 type
      pfam00856
      Location:214319
      SET; SET domain
      pfam12171
      Location:351370
      zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding
      pfam16638
      Location:399504
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
    8. XM_006510466.2XP_006510529.1  PR domain zinc finger protein 10 isoform X1

      See identical proteins and their annotated locations for XP_006510529.1

      Conserved Domains (4) summary
      sd00017
      Location:612632
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:638660
      zf-C2H2; Zinc finger, C2H2 type
      pfam00856
      Location:214319
      SET; SET domain
      pfam16638
      Location:399504
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
    9. XM_006510465.3XP_006510528.1  PR domain zinc finger protein 10 isoform X1

      See identical proteins and their annotated locations for XP_006510528.1

      Conserved Domains (4) summary
      sd00017
      Location:612632
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:638660
      zf-C2H2; Zinc finger, C2H2 type
      pfam00856
      Location:214319
      SET; SET domain
      pfam16638
      Location:399504
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers

    RNA

    1. XR_870532.2 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_199315.1: Suppressed sequence

      Description
      NM_199315.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.
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