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    Prdm10 PR domain containing 10 [ Mus musculus (house mouse) ]

    Gene ID: 382066, updated on 23-Jun-2021

    Summary

    Official Symbol
    Prdm10provided by MGI
    Official Full Name
    PR domain containing 10provided by MGI
    Primary source
    MGI:MGI:2682952
    See related
    Ensembl:ENSMUSG00000042496
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    tr; Gm1112; tristanin
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 3.0), CNS E14 (RPKM 3.0) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Prdm10 in Genome Data Viewer
    Location:
    9; 9 A4
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (31187406..31293027)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (31276110..31381731)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (31122692..31186128)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53544 Neighboring gene predicted gene 7244 Neighboring gene predicted gene, 51733 Neighboring gene predicted gene 10910 Neighboring gene RIKEN cDNA 1700023A20 gene Neighboring gene nuclear factor related to kappa B binding protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC73898

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within methylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of transcription repressor complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    PR domain zinc finger protein 10
    Names
    PR domain-containing protein 10
    NP_001355774.1
    NP_001355775.1
    NP_955019.1
    XP_006510527.1
    XP_006510528.1
    XP_006510529.1
    XP_006510530.1
    XP_006510531.1
    XP_006510532.1
    XP_006510533.1
    XP_006510534.1
    XP_011240870.1
    XP_030100292.1
    XP_030100293.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001368845.1NP_001355774.1  PR domain zinc finger protein 10 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC167244
      Conserved Domains (7) summary
      PRK03427
      Location:9091007
      PRK03427; cell division protein ZipA; Provisional
      sd00017
      Location:612632
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:638660
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:568593
      zf-H2C2_2; Zinc-finger double domain
      pfam16638
      Location:399504
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
      pfam18445
      Location:167194
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19194
      Location:197328
      PR-SET_PRDM10; PR-SET domain found in PR domain zinc finger protein 10 (PRDM10) and similar proteins
    2. NM_001368846.1NP_001355775.1  PR domain zinc finger protein 10 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC167244
      Related
      ENSMUSP00000149526.2, ENSMUST00000215499.2
      Conserved Domains (7) summary
      PRK03427
      Location:9051003
      PRK03427; cell division protein ZipA; Provisional
      sd00017
      Location:608628
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:634656
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:564589
      zf-H2C2_2; Zinc-finger double domain
      pfam16638
      Location:399504
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
      pfam18445
      Location:167194
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19194
      Location:197328
      PR-SET_PRDM10; PR-SET domain found in PR domain zinc finger protein 10 (PRDM10) and similar proteins
    3. NM_199315.2NP_955019.1  PR domain zinc finger protein 10 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC167244, CT025678
      Consensus CDS
      CCDS90529.1
      Related
      ENSMUSP00000112588.2, ENSMUST00000117389.8
      Conserved Domains (2) summary
      pfam18445
      Location:167194
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19194
      Location:197317
      PR-SET_PRDM10; PR-SET domain found in PR domain zinc finger protein 10 (PRDM10) and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      31187406..31293027
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006510464.4XP_006510527.1  PR domain zinc finger protein 10 isoform X1

      See identical proteins and their annotated locations for XP_006510527.1

      Conserved Domains (7) summary
      PRK03427
      Location:9091007
      PRK03427; cell division protein ZipA; Provisional
      sd00017
      Location:612632
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:638660
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:568593
      zf-H2C2_2; Zinc-finger double domain
      pfam16638
      Location:399504
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
      pfam18445
      Location:167194
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19194
      Location:197328
      PR-SET_PRDM10; PR-SET domain found in PR domain zinc finger protein 10 (PRDM10) and similar proteins
    2. XM_006510471.4XP_006510534.1  PR domain zinc finger protein 10 isoform X6

      Conserved Domains (8) summary
      PRK03427
      Location:789887
      PRK03427; cell division protein ZipA; Provisional
      sd00017
      Location:520540
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:518540
      zf-C2H2; Zinc finger, C2H2 type
      pfam12171
      Location:351370
      zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding
      pfam13465
      Location:504527
      zf-H2C2_2; Zinc-finger double domain
      pfam16638
      Location:399504
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
      pfam18445
      Location:167194
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19194
      Location:197328
      PR-SET_PRDM10; PR-SET domain found in PR domain zinc finger protein 10 (PRDM10) and similar proteins
    3. XM_006510468.4XP_006510531.1  PR domain zinc finger protein 10 isoform X3

      Conserved Domains (7) summary
      PRK03427
      Location:901999
      PRK03427; cell division protein ZipA; Provisional
      sd00017
      Location:604624
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:630652
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:560585
      zf-H2C2_2; Zinc-finger double domain
      pfam16638
      Location:399496
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
      pfam18445
      Location:167194
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19194
      Location:197328
      PR-SET_PRDM10; PR-SET domain found in PR domain zinc finger protein 10 (PRDM10) and similar proteins
    4. XM_030244432.1XP_030100292.1  PR domain zinc finger protein 10 isoform X7

      Conserved Domains (8) summary
      PRK03427
      Location:781879
      PRK03427; cell division protein ZipA; Provisional
      sd00017
      Location:512532
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:510532
      zf-C2H2; Zinc finger, C2H2 type
      pfam12171
      Location:351370
      zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding
      pfam13465
      Location:496519
      zf-H2C2_2; Zinc-finger double domain
      pfam16638
      Location:399496
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
      pfam18445
      Location:167194
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19194
      Location:197328
      PR-SET_PRDM10; PR-SET domain found in PR domain zinc finger protein 10 (PRDM10) and similar proteins
    5. XM_006510470.4XP_006510533.1  PR domain zinc finger protein 10 isoform X5

      Conserved Domains (8) summary
      PRK03427
      Location:841939
      PRK03427; cell division protein ZipA; Provisional
      sd00017
      Location:544564
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:570592
      zf-C2H2; Zinc finger, C2H2 type
      pfam12171
      Location:283302
      zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding
      pfam13465
      Location:500525
      zf-H2C2_2; Zinc-finger double domain
      pfam16638
      Location:331436
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
      pfam18445
      Location:167194
      zf_PR_Knuckle; PR zinc knuckle motif
      cl40432
      Location:197260
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily
    6. XM_006510469.4XP_006510532.1  PR domain zinc finger protein 10 isoform X4

      Conserved Domains (7) summary
      PRK03427
      Location:884982
      PRK03427; cell division protein ZipA; Provisional
      sd00017
      Location:587607
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:613635
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:543568
      zf-H2C2_2; Zinc-finger double domain
      pfam16638
      Location:374479
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
      pfam18445
      Location:142169
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19194
      Location:172303
      PR-SET_PRDM10; PR-SET domain found in PR domain zinc finger protein 10 (PRDM10) and similar proteins
    7. XM_006510467.4XP_006510530.1  PR domain zinc finger protein 10 isoform X2

      Conserved Domains (7) summary
      PRK03427
      Location:9051003
      PRK03427; cell division protein ZipA; Provisional
      sd00017
      Location:608628
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:634656
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:564589
      zf-H2C2_2; Zinc-finger double domain
      pfam16638
      Location:399504
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
      pfam18445
      Location:167194
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19194
      Location:197328
      PR-SET_PRDM10; PR-SET domain found in PR domain zinc finger protein 10 (PRDM10) and similar proteins
    8. XM_011242568.3XP_011240870.1  PR domain zinc finger protein 10 isoform X8

      Conserved Domains (7) summary
      COG5048
      Location:553629
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:526546
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam12171
      Location:351370
      zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding
      pfam13465
      Location:568593
      zf-H2C2_2; Zinc-finger double domain
      pfam16638
      Location:399504
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
      pfam18445
      Location:167194
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19194
      Location:197328
      PR-SET_PRDM10; PR-SET domain found in PR domain zinc finger protein 10 (PRDM10) and similar proteins
    9. XM_030244433.2XP_030100293.1  PR domain zinc finger protein 10 isoform X9

      Conserved Domains (2) summary
      pfam18445
      Location:167194
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19194
      Location:197317
      PR-SET_PRDM10; PR-SET domain found in PR domain zinc finger protein 10 (PRDM10) and similar proteins
    10. XM_006510466.4XP_006510529.1  PR domain zinc finger protein 10 isoform X1

      See identical proteins and their annotated locations for XP_006510529.1

      Conserved Domains (7) summary
      PRK03427
      Location:9091007
      PRK03427; cell division protein ZipA; Provisional
      sd00017
      Location:612632
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:638660
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:568593
      zf-H2C2_2; Zinc-finger double domain
      pfam16638
      Location:399504
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
      pfam18445
      Location:167194
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19194
      Location:197328
      PR-SET_PRDM10; PR-SET domain found in PR domain zinc finger protein 10 (PRDM10) and similar proteins
    11. XM_006510465.4XP_006510528.1  PR domain zinc finger protein 10 isoform X1

      See identical proteins and their annotated locations for XP_006510528.1

      Conserved Domains (7) summary
      PRK03427
      Location:9091007
      PRK03427; cell division protein ZipA; Provisional
      sd00017
      Location:612632
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:638660
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:568593
      zf-H2C2_2; Zinc-finger double domain
      pfam16638
      Location:399504
      Tristanin_u2; Unstructured region on methyltransferase between zinc-fingers
      pfam18445
      Location:167194
      zf_PR_Knuckle; PR zinc knuckle motif
      cd19194
      Location:197328
      PR-SET_PRDM10; PR-SET domain found in PR domain zinc finger protein 10 (PRDM10) and similar proteins

    RNA

    1. XR_004935468.1 RNA Sequence

    2. XR_870532.3 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001080817.1: Suppressed sequence

      Description
      NM_001080817.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
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