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    N4bp2l2 NEDD4 binding protein 2-like 2 [ Mus musculus (house mouse) ]

    Gene ID: 381695, updated on 22-May-2018

    Summary

    Official Symbol
    N4bp2l2provided by MGI
    Official Full Name
    NEDD4 binding protein 2-like 2provided by MGI
    Primary source
    MGI:MGI:2687207
    See related
    Ensembl:ENSMUSG00000029655 Vega:OTTMUSG00000027925
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    zag1; Gm38758; 2700092H06Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 3.7), CNS E18 (RPKM 3.4) and 25 other tissues See more
    Orthologs

    Genomic context

    See N4bp2l2 in Genome Data Viewer
    Location:
    5; 5 G3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (150599931..150665612, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (151438548..151468187, complement)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene breast cancer 2, early onset Neighboring gene predicted gene 42529 Neighboring gene NEDD4 binding protein 2-like 1 Neighboring gene predicted gene, 40353 Neighboring gene PDS5 cohesin associated factor B Neighboring gene predicted gene, 36447

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    General gene information

    Markers

    Homology

    Clone Names

    • MGC25830

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcription corepressor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    transcriptional repressor complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    NEDD4-binding protein 2-like 2
    Names
    phosphonoformate immuno-associated protein 5 homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362416.1NP_001349345.1  NEDD4-binding protein 2-like 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC158558, AK038740, BC062895
      Conserved Domains (1) summary
      pfam13671
      Location:396529
      AAA_33; AAA domain
    2. NM_201369.3NP_958757.2  NEDD4-binding protein 2-like 2 isoform 2

      See identical proteins and their annotated locations for NP_958757.2

      Status: VALIDATED

      Source sequence(s)
      AC158558, AK038740, AW488478, CA556104, CB231597, CD561511, CF724618, CJ162163
      Consensus CDS
      CCDS19888.2
      UniProtKB/Swiss-Prot
      Q8JZS6
      UniProtKB/TrEMBL
      Q8BYP6
      Related
      ENSMUSP00000113895.1, OTTMUSP00000035096, ENSMUST00000118316.7, OTTMUST00000069171
      Conserved Domains (2) summary
      pfam13671
      Location:396529
      AAA_33; AAA domain
      cl17190
      Location:396526
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      150599931..150665612 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017320947.1XP_017176436.1  NEDD4-binding protein 2-like 2 isoform X1

      Conserved Domains (1) summary
      pfam13671
      Location:396529
      AAA_33; AAA domain
    2. XM_017320948.1XP_017176437.1  NEDD4-binding protein 2-like 2 isoform X1

      Conserved Domains (1) summary
      pfam13671
      Location:396529
      AAA_33; AAA domain
    3. XM_017320949.1XP_017176438.1  NEDD4-binding protein 2-like 2 isoform X2

    4. XM_017320950.1XP_017176439.1  NEDD4-binding protein 2-like 2 isoform X3

    5. XM_017320951.1XP_017176440.1  NEDD4-binding protein 2-like 2 isoform X3

    6. XM_011241035.2XP_011239337.1  NEDD4-binding protein 2-like 2 isoform X4

      See identical proteins and their annotated locations for XP_011239337.1

    7. XM_017320946.1XP_017176435.1  NEDD4-binding protein 2-like 2 isoform X1

      Conserved Domains (1) summary
      pfam13671
      Location:396529
      AAA_33; AAA domain

    RNA

    1. XR_001784715.1 RNA Sequence

    2. XR_001784714.1 RNA Sequence

    3. XR_001784713.1 RNA Sequence

    4. XR_001784712.1 RNA Sequence

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