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    N4bp2l2 NEDD4 binding protein 2-like 2 [ Mus musculus (house mouse) ]

    Gene ID: 381695, updated on 23-Jun-2021

    Summary

    Official Symbol
    N4bp2l2provided by MGI
    Official Full Name
    NEDD4 binding protein 2-like 2provided by MGI
    Primary source
    MGI:MGI:2687207
    See related
    Ensembl:ENSMUSG00000029655
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    zag; zag1; Gm38758; 2700092H06Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 3.7), CNS E18 (RPKM 3.4) and 25 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See N4bp2l2 in Genome Data Viewer
    Location:
    5; 5 G3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (150515310..150589213, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (150599931..150665748, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (151438548..151468187, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene breast cancer 2, early onset Neighboring gene predicted gene, 23641 Neighboring gene predicted gene 42529 Neighboring gene NEDD4 binding protein 2-like 1 Neighboring gene predicted gene, 40353 Neighboring gene PDS5 cohesin associated factor B Neighboring gene predicted gene, 24630

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC25830

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transcription corepressor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of transcription repressor complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    NEDD4-binding protein 2-like 2
    Names
    phosphonoformate immuno-associated protein 5 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362416.1NP_001349345.1  NEDD4-binding protein 2-like 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC158558, AK038740, BC062895
      Conserved Domains (1) summary
      pfam13671
      Location:396529
      AAA_33; AAA domain
    2. NM_201369.3NP_958757.2  NEDD4-binding protein 2-like 2 isoform 2

      See identical proteins and their annotated locations for NP_958757.2

      Status: VALIDATED

      Source sequence(s)
      AC158558, AK038740, AW488478, CA556104, CB231597, CD561511, CF724618, CJ162163
      Consensus CDS
      CCDS19888.2
      UniProtKB/Swiss-Prot
      Q8JZS6
      UniProtKB/TrEMBL
      Q8BYP6
      Related
      ENSMUSP00000113895.2, ENSMUST00000118316.8
      Conserved Domains (2) summary
      pfam13671
      Location:396529
      AAA_33; AAA domain
      cl17190
      Location:396526
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      150515310..150589213 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030254630.2XP_030110490.1  NEDD4-binding protein 2-like 2 isoform X1

      Conserved Domains (1) summary
      pfam13671
      Location:396529
      AAA_33; AAA domain
    2. XM_030254629.2XP_030110489.1  NEDD4-binding protein 2-like 2 isoform X1

      Conserved Domains (1) summary
      pfam13671
      Location:396529
      AAA_33; AAA domain
    3. XM_036165248.1XP_036021141.1  NEDD4-binding protein 2-like 2 isoform X1

      Conserved Domains (1) summary
      pfam13671
      Location:396529
      AAA_33; AAA domain
    4. XM_036165249.1XP_036021142.1  NEDD4-binding protein 2-like 2 isoform X1

      Conserved Domains (1) summary
      pfam13671
      Location:396529
      AAA_33; AAA domain
    5. XM_036165251.1XP_036021144.1  NEDD4-binding protein 2-like 2 isoform X1

      Conserved Domains (1) summary
      pfam13671
      Location:396529
      AAA_33; AAA domain
    6. XM_036165252.1XP_036021145.1  NEDD4-binding protein 2-like 2 isoform X2

      Conserved Domains (1) summary
      pfam13671
      Location:1793
      AAA_33; AAA domain
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