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    Zfp408 zinc finger protein 408 [ Mus musculus (house mouse) ]

    Gene ID: 381410, updated on 23-Jun-2021

    Summary

    Official Symbol
    Zfp408provided by MGI
    Official Full Name
    zinc finger protein 408provided by MGI
    Primary source
    MGI:MGI:2685857
    See related
    Ensembl:ENSMUSG00000075040
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm1011
    Expression
    Ubiquitous expression in thymus adult (RPKM 13.6), ovary adult (RPKM 8.7) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Zfp408 in Genome Data Viewer
    Location:
    2; 2 E1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (91473101..91480399, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (91642756..91650051, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (91483845..91489948, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene cytoskeleton associated protein 5 Neighboring gene coagulation factor II Neighboring gene cytochrome c oxidase subunit 7B, mitochondrial pseudogene Neighboring gene Rho GTPase activating protein 1 Neighboring gene autophagy related 13

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033451.3NP_001028623.1  zinc finger protein 408 isoform 2

      See identical proteins and their annotated locations for NP_001028623.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate segment that results in the use of a downstream AUG compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1.
      Source sequence(s)
      AK132515, BF459039
      Consensus CDS
      CCDS16436.1
      UniProtKB/TrEMBL
      Q3V1D8
      Related
      ENSMUSP00000106965.2, ENSMUST00000111333.2
      Conserved Domains (3) summary
      COG5048
      Location:158407
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:361381
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl40432
      Location:372
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily
    2. NM_001347175.2NP_001334104.1  zinc finger protein 408 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL691489
      Consensus CDS
      CCDS84551.1
      UniProtKB/TrEMBL
      H7BX78
      Related
      ENSMUSP00000097301.4, ENSMUST00000099714.10

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      91473101..91480399 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036162345.1XP_036018238.1  zinc finger protein 408 isoform X1

      Conserved Domains (3) summary
      COG5048
      Location:158407
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:361381
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl40432
      Location:372
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily
    2. XM_030251819.1XP_030107679.1  zinc finger protein 408 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:33282
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:236256
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. XM_030251815.2XP_030107675.1  zinc finger protein 408 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:33282
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:236256
      ZF_C2H2; C2H2 Zn finger [structural motif]
    4. XM_036162346.1XP_036018239.1  zinc finger protein 408 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:33282
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:236256
      ZF_C2H2; C2H2 Zn finger [structural motif]
    5. XM_011239644.4XP_011237946.1  zinc finger protein 408 isoform X2

      See identical proteins and their annotated locations for XP_011237946.1

      Conserved Domains (2) summary
      COG5048
      Location:33282
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:236256
      ZF_C2H2; C2H2 Zn finger [structural motif]
    6. XM_006499832.3XP_006499895.1  zinc finger protein 408 isoform X2

      See identical proteins and their annotated locations for XP_006499895.1

      Conserved Domains (2) summary
      COG5048
      Location:33282
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:236256
      ZF_C2H2; C2H2 Zn finger [structural motif]
    7. XM_030251818.1XP_030107678.1  zinc finger protein 408 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:33282
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:236256
      ZF_C2H2; C2H2 Zn finger [structural motif]
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