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    Tbc1d22b TBC1 domain family, member 22B [ Mus musculus (house mouse) ]

    Gene ID: 381085, updated on 5-Aug-2018

    Summary

    Official Symbol
    Tbc1d22bprovided by MGI
    Official Full Name
    TBC1 domain family, member 22Bprovided by MGI
    Primary source
    MGI:MGI:2681867
    See related
    Ensembl:ENSMUSG00000042203 Vega:OTTMUSG00000034448
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BC045600
    Expression
    Ubiquitous expression in thymus adult (RPKM 16.0), adrenal adult (RPKM 12.8) and 28 other tissues See more
    Orthologs

    Genomic context

    See Tbc1d22b in Genome Data Viewer
    Location:
    17; 17 A3.3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (29549788..29606894)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (29686747..29743753)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene proviral integration site 1 Neighboring gene transmembrane protein 217 Neighboring gene TBC1 domain family, member 22B, opposite strand Neighboring gene microRNA 7667 Neighboring gene predicted gene, 28043 Neighboring gene ring finger protein 8 Neighboring gene predicted gene, 20161

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC31516, MGC61359

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    14-3-3 protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Rab GTPase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    activation of GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    TBC1 domain family member 22B

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198647.1NP_941049.1  TBC1 domain family member 22B

      See identical proteins and their annotated locations for NP_941049.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045600
      Consensus CDS
      CCDS28597.1
      UniProtKB/TrEMBL
      Q80VE5
      Related
      ENSMUSP00000046877.7, OTTMUSP00000047544, ENSMUST00000048677.7, OTTMUST00000087478
      Conserved Domains (1) summary
      smart00164
      Location:207457
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      29549788..29606894
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006524488.1XP_006524551.1  TBC1 domain family member 22B isoform X1

      Conserved Domains (1) summary
      smart00164
      Location:188438
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
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