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    TMEM179B transmembrane protein 179B [ Homo sapiens (human) ]

    Gene ID: 374395, updated on 7-Apr-2024

    Summary

    Official Symbol
    TMEM179Bprovided by HGNC
    Official Full Name
    transmembrane protein 179Bprovided by HGNC
    Primary source
    HGNC:HGNC:33744
    See related
    Ensembl:ENSG00000185475 AllianceGenome:HGNC:33744
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Located in nuclear speck and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in prostate (RPKM 21.9), thyroid (RPKM 20.8) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See TMEM179B in Genome Data Viewer
    Location:
    11q12.3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (62787402..62790400)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (62776793..62779792)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (62554874..62557872)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4844 Neighboring gene RNA polymerase II subunit G Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4845 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3429 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4846 Neighboring gene transmembrane protein 223 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4847 Neighboring gene TATA-box binding protein associated factor 6 like Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4848 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3430 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4849 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3431 Neighboring gene microRNA 6748 Neighboring gene microRNA 6514 Neighboring gene nuclear RNA export factor 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:62572705-62573204 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4850 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4851 Neighboring gene syntaxin 5 Neighboring gene RNA, U6 small nuclear 118, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001363599.1NP_001350528.1  transmembrane protein 179B isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AP001160
      Consensus CDS
      CCDS91494.1
      UniProtKB/TrEMBL
      G3V185
      Related
      ENSP00000433055.1, ENST00000533861.5
    2. NM_001363600.1NP_001350529.1  transmembrane protein 179B isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      AP001160
    3. NM_001363601.1NP_001350530.1  transmembrane protein 179B isoform 4

      Status: VALIDATED

      Source sequence(s)
      AP001160
    4. NM_199337.3NP_955369.1  transmembrane protein 179B isoform 1 precursor

      See identical proteins and their annotated locations for NP_955369.1

      Status: VALIDATED

      Source sequence(s)
      BC051355, BE439533, BM684628
      Consensus CDS
      CCDS8036.1
      UniProtKB/Swiss-Prot
      Q7Z7N9
      Related
      ENSP00000333697.3, ENST00000333449.9

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      62787402..62790400
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      62776793..62779792
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)