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    H3c1 H3 clustered histone 1 [ Mus musculus (house mouse) ]

    Gene ID: 360198, updated on 23-Jun-2021

    Summary

    Official Symbol
    H3c1provided by MGI
    Official Full Name
    H3 clustered histone 1provided by MGI
    Primary source
    MGI:MGI:2668828
    See related
    Ensembl:ENSMUSG00000069265
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    H3c8; H3c10; H3c11; Hist1; Hist1h3a
    Summary
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Aug 2015]
    Orthologs
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    Genomic context

    See H3c1 in Genome Data Viewer
    Location:
    13; 13 A3.1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (23945868..23946369, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (23761885..23762386, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (23853722..23854255, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene H4 clustered histone 2 Neighboring gene H4 clustered histone 1 Neighboring gene H1.1 linker histone, cluster member Neighboring gene tripartite motif-containing 38

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in DNA replication-dependent nucleosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nucleosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of gene silencing ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in nuclear chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nucleosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    histone H3.1
    Names
    histone 1, H3a
    histone cluster 1, H3a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013550.5NP_038578.2  histone H3.1

      See identical proteins and their annotated locations for NP_038578.2

      Status: REVIEWED

      Source sequence(s)
      AL590388
      Consensus CDS
      CCDS26368.1
      UniProtKB/Swiss-Prot
      P68433
      Related
      ENSMUSP00000089293.3, ENSMUST00000091701.3
      Conserved Domains (1) summary
      PTZ00018
      Location:1136
      PTZ00018; histone H3; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      23945868..23946369 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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