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    KRTAP10-10 keratin associated protein 10-10 [ Homo sapiens (human) ]

    Gene ID: 353333, updated on 17-Sep-2024

    Summary

    Official Symbol
    KRTAP10-10provided by HGNC
    Official Full Name
    keratin associated protein 10-10provided by HGNC
    Primary source
    HGNC:HGNC:22972
    See related
    Ensembl:ENSG00000221859 AllianceGenome:HGNC:22972
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    KAP10.10; KAP18.10; KRTAP18-10; KRTAP18.10
    Summary
    Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See KRTAP10-10 in Genome Data Viewer
    Location:
    21q22.3
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (44637356..44638455)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (42997807..42998906)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (46057273..46058372)

    Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene thrombospondin type laminin G domain and EAR repeats Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46031985-46032634 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46032635-46033283 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46036915-46037661 Neighboring gene keratin associated protein 10-8 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:46045935-46046630 Neighboring gene keratin associated protein 10-9 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:46067006-46067870 Neighboring gene keratin associated protein 10-11 Neighboring gene keratin associated protein 12-4

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in keratin filament IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    keratin-associated protein 10-10
    Names
    high sulfur keratin-associated protein 10.10
    keratin-associated protein 18-10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_181688.3NP_859016.1  keratin-associated protein 10-10

      See identical proteins and their annotated locations for NP_859016.1

      Status: VALIDATED

      Source sequence(s)
      AJ566387, AL773602
      Consensus CDS
      CCDS33585.1
      UniProtKB/Swiss-Prot
      P60014
      Related
      ENSP00000369438.1, ENST00000380095.2
      Conserved Domains (2) summary
      pfam01500
      Location:114245
      Keratin_B2; Keratin, high sulfur B2 protein
      pfam13885
      Location:146197
      Keratin_B2_2; Keratin, high sulfur B2 protein

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

      Range
      44637356..44638455
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060945.1 Alternate T2T-CHM13v2.0

      Range
      42997807..42998906
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)