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    TCEAL5 transcription elongation factor A like 5 [ Homo sapiens (human) ]

    Gene ID: 340543, updated on 17-Jun-2024

    Summary

    Official Symbol
    TCEAL5provided by HGNC
    Official Full Name
    transcription elongation factor A like 5provided by HGNC
    Primary source
    HGNC:HGNC:22282
    See related
    Ensembl:ENSG00000204065 AllianceGenome:HGNC:22282
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    WEX4
    Summary
    This gene, which is located on the X chromosome, encodes a protein which contains a BEX (brain expressed X-liked like family) domain. This domain is found in proteins encoded by the TCEAL elongation factor (transcription elongation factor A (SII)-like) gene family also located on the X chromosome. The coding region for this gene is located entirely in the terminal exon. [provided by RefSeq, Sep 2011]
    Expression
    Biased expression in testis (RPKM 33.5), brain (RPKM 32.2) and 3 other tissues See more
    Orthologs
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    Genomic context

    See TCEAL5 in Genome Data Viewer
    Location:
    Xq22.1
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (103273691..103276750, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (101720668..101723727, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (102528619..102531678, complement)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29816 Neighboring gene guanosine monophosphate reductase pseudogene Neighboring gene transcription elongation factor A like 8 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20920 Neighboring gene brain expressed X-linked 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:102585683-102586182 Neighboring gene transcription elongation factor A like 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    transcription elongation factor A protein-like 5
    Names
    TCEA-like protein 5
    transcription elongation factor A (SII)-like 5
    transcription elongation factor S-II protein-like 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_016591.1 RefSeqGene

      Range
      5120..8179
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001012979.3NP_001012997.1  transcription elongation factor A protein-like 5

      See identical proteins and their annotated locations for NP_001012997.1

      Status: REVIEWED

      Source sequence(s)
      BC132924, BM725918, Z68694
      Consensus CDS
      CCDS35356.1
      UniProtKB/Swiss-Prot
      A2RUJ4, Q5H9L2
      Related
      ENSP00000361765.1, ENST00000372680.2
      Conserved Domains (2) summary
      pfam04538
      Location:87179
      BEX; Brain expressed X-linked like family
      cl27511
      Location:6166
      Na_Ca_ex; Sodium/calcium exchanger protein

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      103273691..103276750 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      101720668..101723727 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)