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    H3Y2 H3.Y histone 2 [ Homo sapiens (human) ]

    Gene ID: 340096, updated on 5-Mar-2024

    Summary

    Official Symbol
    H3Y2provided by HGNC
    Official Full Name
    H3.Y histone 2provided by HGNC
    Primary source
    HGNC:HGNC:43734
    See related
    Ensembl:ENSG00000268799 AllianceGenome:HGNC:43734
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    H3.X; H3.Y.2
    Summary
    Predicted to enable DNA binding activity and protein heterodimerization activity. Part of nucleosome. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See H3Y2 in Genome Data Viewer
    Location:
    5p15.1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (17490967..17492076, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (17430381..17431490, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (17491076..17492185, complement)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 2218 Neighboring gene TATA-box binding protein associated factor 11 like 1 (pseudogene) Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:17501918-17502418 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:17502419-17502919 Neighboring gene TATA-box binding protein associated factor 11 like 2 Neighboring gene H3 histone pseudogene 18

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    part_of nucleosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    histone H3.X
    Names
    H3 histone, family 3B (H3.3B) pseudogene
    Putative histone H3.X
    histone H3.Y2
    histone cluster 2, H3d pseudogene

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001371919.1NP_001358848.1  histone H3.X

      Status: VALIDATED

      Source sequence(s)
      AC106774
      Consensus CDS
      CCDS93687.1
      UniProtKB/Swiss-Prot
      P0DPK5
      Related
      ENSP00000497053.1, ENST00000600799.3
      Conserved Domains (1) summary
      PTZ00018
      Location:1134
      PTZ00018; histone H3; Provisional

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      17490967..17492076 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      17430381..17431490 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_023411.2: Suppressed sequence

      Description
      NG_023411.2: This RefSeq was removed because it is now thought that this gene does encode a protein.