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    N4bp2 NEDD4 binding protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 333789, updated on 5-Aug-2018

    Summary

    Official Symbol
    N4bp2provided by MGI
    Official Full Name
    NEDD4 binding protein 2provided by MGI
    Primary source
    MGI:MGI:2684414
    See related
    Ensembl:ENSMUSG00000037795 Vega:OTTMUSG00000022204
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    B3bp; Gm868; Gm1791; E430014I16
    Expression
    Broad expression in CNS E11.5 (RPKM 6.8), limb E14.5 (RPKM 6.3) and 27 other tissues See more
    Orthologs

    Genomic context

    See N4bp2 in Genome Data Viewer
    Location:
    5; 5 C3.1
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (65763291..65830107)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (66154760..66218023)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene PDS5 cohesin associated factor A Neighboring gene predicted gene, 46945 Neighboring gene uncharacterized LOC102634968 Neighboring gene ras homolog family member H

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding ISO
    Inferred from Sequence Orthology
    more info
     
    ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    endonuclease activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    NEDD4-binding protein 2
    Names
    Bcl3 binding protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024917.1NP_001020088.1  NEDD4-binding protein 2

      See identical proteins and their annotated locations for NP_001020088.1

      Status: VALIDATED

      Source sequence(s)
      AK173167, BC054549, CK637074, CX769144
      Consensus CDS
      CCDS19310.1
      UniProtKB/TrEMBL
      F8VQG7, Q69ZK1
      Related
      ENSMUSP00000143807.1, OTTMUSP00000025061, ENSMUST00000201489.3, OTTMUST00000052767
      Conserved Domains (3) summary
      smart00463
      Location:15961678
      SMR; Small MutS-related domain
      pfam08590
      Location:15291588
      DUF1771; Domain of unknown function (DUF1771)
      pfam13671
      Location:372498
      AAA_33; AAA domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      65763291..65830107
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006504004.3XP_006504067.1  NEDD4-binding protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006504067.1

      Conserved Domains (4) summary
      smart00463
      Location:17031785
      SMR; Small MutS-related domain
      cd14365
      Location:74114
      CUE_N4BP2; CUE domain found in NEDD4-binding protein 2 (N4BP2) and similar proteins
      pfam08590
      Location:16361695
      DUF1771; Domain of unknown function (DUF1771)
      pfam13671
      Location:479605
      AAA_33; AAA domain
    2. XM_006504007.2XP_006504070.1  NEDD4-binding protein 2 isoform X3

      See identical proteins and their annotated locations for XP_006504070.1

      UniProtKB/TrEMBL
      F8VQG7
      Related
      ENSMUSP00000084519.3, ENSMUST00000087264.3
      Conserved Domains (3) summary
      smart00463
      Location:15961678
      SMR; Small MutS-related domain
      pfam08590
      Location:15291588
      DUF1771; Domain of unknown function (DUF1771)
      pfam13671
      Location:372498
      AAA_33; AAA domain
    3. XM_006504003.2XP_006504066.1  NEDD4-binding protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006504066.1

      Conserved Domains (4) summary
      smart00463
      Location:17031785
      SMR; Small MutS-related domain
      cd14365
      Location:74114
      CUE_N4BP2; CUE domain found in NEDD4-binding protein 2 (N4BP2) and similar proteins
      pfam08590
      Location:16361695
      DUF1771; Domain of unknown function (DUF1771)
      pfam13671
      Location:479605
      AAA_33; AAA domain
    4. XM_006504006.3XP_006504069.1  NEDD4-binding protein 2 isoform X2

      Conserved Domains (4) summary
      smart00463
      Location:16761758
      SMR; Small MutS-related domain
      cd14365
      Location:4787
      CUE_N4BP2; CUE domain found in NEDD4-binding protein 2 (N4BP2) and similar proteins
      pfam08590
      Location:16091668
      DUF1771; Domain of unknown function (DUF1771)
      pfam13671
      Location:452578
      AAA_33; AAA domain
    5. XM_011240752.2XP_011239054.1  NEDD4-binding protein 2 isoform X1

      See identical proteins and their annotated locations for XP_011239054.1

      Conserved Domains (4) summary
      smart00463
      Location:17031785
      SMR; Small MutS-related domain
      cd14365
      Location:74114
      CUE_N4BP2; CUE domain found in NEDD4-binding protein 2 (N4BP2) and similar proteins
      pfam08590
      Location:16361695
      DUF1771; Domain of unknown function (DUF1771)
      pfam13671
      Location:479605
      AAA_33; AAA domain
    6. XM_006504005.3XP_006504068.1  NEDD4-binding protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006504068.1

      Conserved Domains (4) summary
      smart00463
      Location:17031785
      SMR; Small MutS-related domain
      cd14365
      Location:74114
      CUE_N4BP2; CUE domain found in NEDD4-binding protein 2 (N4BP2) and similar proteins
      pfam08590
      Location:16361695
      DUF1771; Domain of unknown function (DUF1771)
      pfam13671
      Location:479605
      AAA_33; AAA domain
    7. XM_006504008.3XP_006504071.1  NEDD4-binding protein 2 isoform X3

      See identical proteins and their annotated locations for XP_006504071.1

      UniProtKB/TrEMBL
      F8VQG7
      Conserved Domains (3) summary
      smart00463
      Location:15961678
      SMR; Small MutS-related domain
      pfam08590
      Location:15291588
      DUF1771; Domain of unknown function (DUF1771)
      pfam13671
      Location:372498
      AAA_33; AAA domain
    8. XM_017320936.1XP_017176425.1  NEDD4-binding protein 2 isoform X3

      UniProtKB/TrEMBL
      F8VQG7
      Conserved Domains (3) summary
      smart00463
      Location:15961678
      SMR; Small MutS-related domain
      pfam08590
      Location:15291588
      DUF1771; Domain of unknown function (DUF1771)
      pfam13671
      Location:372498
      AAA_33; AAA domain
    9. XM_017320937.1XP_017176426.1  NEDD4-binding protein 2 isoform X4

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