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    Gpd1l glycerol-3-phosphate dehydrogenase 1-like [ Mus musculus (house mouse) ]

    Gene ID: 333433, updated on 23-Jun-2021

    Summary

    Official Symbol
    Gpd1lprovided by MGI
    Official Full Name
    glycerol-3-phosphate dehydrogenase 1-likeprovided by MGI
    Primary source
    MGI:MGI:1289257
    See related
    Ensembl:ENSMUSG00000050627
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D9Ertd660; D9Ertd660e; 2210409H23Rik
    Expression
    Ubiquitous expression in cortex adult (RPKM 16.6), large intestine adult (RPKM 16.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Gpd1l in Genome Data Viewer
    Location:
    9 F3; 9 65.47 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (114728407..114763055, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (114899339..114933987, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (114808457..114843105, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene CKLF-like MARVEL transmembrane domain containing 8 Neighboring gene predicted gene, 23889 Neighboring gene predicted gene, 30448 Neighboring gene oxysterol binding protein-like 10 Neighboring gene ribosomal protein S27, retrogene Neighboring gene predicted gene 4665

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
     
    NOT enables glycerol-3-phosphate dehydrogenase [NAD+] activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables sodium channel regulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transmembrane transporter binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in NAD metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within NADH metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    NOT involved_in NADH oxidation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glycerol-3-phosphate catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glycerol-3-phosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of peptidyl-serine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of protein kinase C signaling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of protein localization to cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of sodium ion transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of heart rate ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of sodium ion transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of ventricular cardiac muscle cell membrane depolarization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ventricular cardiac muscle cell action potential ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of glycerol-3-phosphate dehydrogenase complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    glycerol-3-phosphate dehydrogenase 1-like protein
    NP_780589.3
    XP_036010981.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175380.5NP_780589.3  glycerol-3-phosphate dehydrogenase 1-like protein

      See identical proteins and their annotated locations for NP_780589.3

      Status: VALIDATED

      Source sequence(s)
      AC127573, AK172886, BC138980, BY369485
      Consensus CDS
      CCDS23598.1
      UniProtKB/Swiss-Prot
      Q3ULJ0
      UniProtKB/TrEMBL
      B2RSR7
      Related
      ENSMUSP00000117509.2, ENSMUST00000146623.8
      Conserved Domains (3) summary
      TIGR03376
      Location:7344
      glycerol3P_DH; glycerol-3-phosphate dehydrogenase (NAD(+))
      pfam01210
      Location:7175
      NAD_Gly3P_dh_N; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
      pfam07479
      Location:198337
      NAD_Gly3P_dh_C; NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      114728407..114763055 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036155088.1XP_036010981.1  glycerol-3-phosphate dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      TIGR03376
      Location:1305
      glycerol3P_DH; glycerol-3-phosphate dehydrogenase (NAD(+))
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