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    Gpd1l glycerol-3-phosphate dehydrogenase 1-like [ Mus musculus (house mouse) ]

    Gene ID: 333433, updated on 31-Jan-2019

    Summary

    Official Symbol
    Gpd1lprovided by MGI
    Official Full Name
    glycerol-3-phosphate dehydrogenase 1-likeprovided by MGI
    Primary source
    MGI:MGI:1289257
    See related
    Ensembl:ENSMUSG00000050627
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D9Ertd660e; 2210409H23Rik
    Expression
    Ubiquitous expression in cortex adult (RPKM 16.6), large intestine adult (RPKM 16.2) and 28 other tissues See more
    Orthologs

    Genomic context

    See Gpd1l in Genome Data Viewer
    Location:
    9 F3; 9 65.47 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (114899339..114933987, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (114808457..114843105, complement)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene CKLF-like MARVEL transmembrane domain containing 8 Neighboring gene predicted gene, 30448 Neighboring gene oxysterol binding protein-like 10 Neighboring gene ribosomal protein S27, retrogene Neighboring gene predicted gene 4665

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    NAD binding IEA
    Inferred from Electronic Annotation
    more info
     
    glycerol-3-phosphate dehydrogenase [NAD+] activity IEA
    Inferred from Electronic Annotation
    more info
     
    ion channel binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ion channel binding ISO
    Inferred from Sequence Orthology
    more info
     
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
    Inferred from Electronic Annotation
    more info
     
    protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    sodium channel regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    sodium channel regulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    NAD metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    NADH metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    action potential IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    glycerol-3-phosphate catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    glycerol-3-phosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of peptidyl-serine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of protein kinase C signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of protein kinase C signaling ISO
    Inferred from Sequence Orthology
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of protein localization to cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of sodium ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of sodium ion transport ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of heart rate ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of sodium ion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of sodium ion transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of ventricular cardiac muscle cell membrane depolarization ISO
    Inferred from Sequence Orthology
    more info
     
    ventricular cardiac muscle cell action potential ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    glycerol-3-phosphate dehydrogenase complex IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    glycerol-3-phosphate dehydrogenase 1-like protein
    NP_780589.3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175380.5NP_780589.3  glycerol-3-phosphate dehydrogenase 1-like protein

      See identical proteins and their annotated locations for NP_780589.3

      Status: VALIDATED

      Source sequence(s)
      AC127573, AK172886, BC138980, BY369485
      Consensus CDS
      CCDS23598.1
      UniProtKB/Swiss-Prot
      Q3ULJ0
      UniProtKB/TrEMBL
      B2RSR7
      Related
      ENSMUSP00000117509.1, ENSMUST00000146623.7
      Conserved Domains (3) summary
      TIGR03376
      Location:7344
      glycerol3P_DH; glycerol-3-phosphate dehydrogenase (NAD(+))
      pfam01210
      Location:7175
      NAD_Gly3P_dh_N; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
      pfam07479
      Location:198337
      NAD_Gly3P_dh_C; NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      114899339..114933987 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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