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    Nlrp9c NLR family, pyrin domain containing 9C [ Mus musculus (house mouse) ]

    Gene ID: 330490, updated on 23-Jun-2021

    Summary

    Official Symbol
    Nlrp9cprovided by MGI
    Official Full Name
    NLR family, pyrin domain containing 9Cprovided by MGI
    Primary source
    MGI:MGI:3028627
    See related
    Ensembl:ENSMUSG00000040614
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Na; Nalp; Nalp9c; AA636537; BB062542; Nalp-zeta
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See Nlrp9c in Genome Data Viewer
    Location:
    7; 7 A3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (26064116..26103125, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (26364691..26403700, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (27149906..27179262, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 1 receptor, 184 Neighboring gene predicted gene, 42375 Neighboring gene cytochrome P450, family 2, subfamily a, polypeptide 4 Neighboring gene NLR family, pyrin domain containing 4A Neighboring gene NLR family, pyrin domain containing 9A

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    acts_upstream_of_or_within immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within inflammatory response IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within innate immune response IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    part_of inflammasome complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    NACHT, LRR and PYD domains-containing protein 9C

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042612.2NP_001036077.1  NACHT, LRR and PYD domains-containing protein 9C

      See identical proteins and their annotated locations for NP_001036077.1

      Status: VALIDATED

      Source sequence(s)
      AC161798, AK087873, AY596203, BB702737
      Consensus CDS
      CCDS39843.1
      UniProtKB/Swiss-Prot
      Q66X01
      Related
      ENSMUSP00000083106.6, ENSMUST00000085944.6
      Conserved Domains (4) summary
      cd00116
      Location:693961
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd08320
      Location:991
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      sd00033
      Location:695723
      LRR_RI; leucine-rich repeat [structural motif]
      pfam05729
      Location:144304
      NACHT; NACHT domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      26064116..26103125 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017322312.1XP_017177801.1  NACHT, LRR and PYD domains-containing protein 9C isoform X1

      Conserved Domains (6) summary
      cd08320
      Location:991
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      sd00033
      Location:695723
      LRR_RI; leucine-rich repeat [structural motif]
      pfam05729
      Location:144304
      NACHT; NACHT domain
      pfam17776
      Location:441556
      NLRC4_HD2; NLRC4 helical domain HD2
      pfam17779
      Location:388431
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:693961
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    2. XM_017322313.1XP_017177802.1  NACHT, LRR and PYD domains-containing protein 9C isoform X2

      Conserved Domains (6) summary
      cd08320
      Location:991
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      sd00033
      Location:640668
      LRR_RI; leucine-rich repeat [structural motif]
      pfam05729
      Location:144304
      NACHT; NACHT domain
      pfam17776
      Location:441556
      NLRC4_HD2; NLRC4 helical domain HD2
      pfam17779
      Location:388431
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:638906
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    3. XM_017322314.1XP_017177803.1  NACHT, LRR and PYD domains-containing protein 9C isoform X3

      Related
      ENSMUSP00000036041.8, ENSMUST00000041845.14
      Conserved Domains (6) summary
      cd08320
      Location:991
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      sd00033
      Location:640668
      LRR_RI; leucine-rich repeat [structural motif]
      pfam05729
      Location:144304
      NACHT; NACHT domain
      pfam17776
      Location:441556
      NLRC4_HD2; NLRC4 helical domain HD2
      pfam17779
      Location:388431
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:634842
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_194062.1: Suppressed sequence

      Description
      NM_194062.1: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript.
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