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    Cecr2 CECR2, histone acetyl-lysine reader [ Mus musculus (house mouse) ]

    Gene ID: 330409, updated on 21-Feb-2019

    Summary

    Official Symbol
    Cecr2provided by MGI
    Official Full Name
    CECR2, histone acetyl-lysine readerprovided by MGI
    Primary source
    MGI:MGI:1923799
    See related
    Ensembl:ENSMUSG00000071226
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gtl4; 2610101O16Rik; 2810409N01Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 4.5), CNS E11.5 (RPKM 4.0) and 23 other tissues See more
    Orthologs

    Genomic context

    See Cecr2 in Genome Data Viewer
    Location:
    6 F1; 6 56.97 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (120666320..120771194)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (120616439..120721209)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene haloacid dehalogenase like hydrolase domain containing 5 Neighboring gene RIKEN cDNA 1700072O05 gene Neighboring gene solute carrier family 25 (mitochondrial carrier), member 18 Neighboring gene ATPase, H+ transporting, lysosomal V1 subunit E1 Neighboring gene ribosomal protein S27 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA1740

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    ATP-dependent chromatin remodeling ISO
    Inferred from Sequence Orthology
    more info
     
    chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    cochlea development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    execution phase of apoptosis ISO
    Inferred from Sequence Orthology
    more info
     
    inner ear receptor cell stereocilium organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neural fold formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neural tube closure IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    neural tube closure IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neural tube development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    single fertilization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    CERF complex ISO
    Inferred from Sequence Orthology
    more info
     
    ISWI-type complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    nuclear euchromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cat eye syndrome critical region protein 2 homolog; cat eye syndrome critical region protein 2
    Names
    cat eye syndrome chromosome region, candidate 2 homolog
    gene trap locus 4

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001128151.2NP_001121623.1  cat eye syndrome critical region protein 2 homolog isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC084273, AC135105
      Consensus CDS
      CCDS51890.1
      UniProtKB/Swiss-Prot
      E9Q2Z1
      Related
      ENSMUSP00000108306.1, ENSMUST00000112686.7
      Conserved Domains (2) summary
      cd05509
      Location:418518
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      pfam15614
      Location:244284
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3
    2. NM_001368706.1NP_001355635.1  cat eye syndrome critical region protein 2 homolog isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC084273, AC135105

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      120666320..120771194
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006506320.1XP_006506383.1  cat eye syndrome critical region protein 2 isoform X1

      UniProtKB/Swiss-Prot
      E9Q2Z1
      Related
      ENSMUSP00000098556.2, ENSMUST00000100993.8
      Conserved Domains (2) summary
      cd05509
      Location:418518
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      cl26464
      Location:5581031
      Atrophin-1; Atrophin-1 family
    2. XM_017321659.1XP_017177148.1  cat eye syndrome critical region protein 2 isoform X2

    3. XM_011241398.1XP_011239700.1  cat eye syndrome critical region protein 2 isoform X5

      See identical proteins and their annotated locations for XP_011239700.1

      Conserved Domains (2) summary
      cd05509
      Location:418518
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      pfam15614
      Location:244284
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3
    4. XM_011241396.1XP_011239698.1  cat eye syndrome critical region protein 2 isoform X3

      See identical proteins and their annotated locations for XP_011239698.1

      Conserved Domains (2) summary
      cd05509
      Location:390490
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      pfam15614
      Location:244284
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3
    5. XM_011241397.2XP_011239699.1  cat eye syndrome critical region protein 2 isoform X4

      See identical proteins and their annotated locations for XP_011239699.1

      Conserved Domains (2) summary
      cd05509
      Location:277377
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      pfam15614
      Location:103143
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3

    Reference GRCm38.p4 129S1/SvImJ

    Genomic

    1. NT_039382.4 Reference GRCm38.p4 129S1/SvImJ

      Range
      289415..394533
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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