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    Slc5a6 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 [ Mus musculus (house mouse) ]

    Gene ID: 330064, updated on 22-Aug-2021

    Summary

    Official Symbol
    Slc5a6provided by MGI
    Official Full Name
    solute carrier family 5 (sodium-dependent vitamin transporter), member 6provided by MGI
    Primary source
    MGI:MGI:2660847
    See related
    Ensembl:ENSMUSG00000006641
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    E430023I20
    Expression
    Ubiquitous expression in mammary gland adult (RPKM 20.8), large intestine adult (RPKM 17.4) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Slc5a6 in Genome Data Viewer
    Location:
    5; 5 B1
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (31193380..31206268, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (31036036..31048924, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (31338409..31351297, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene abhydrolase domain containing 1 Neighboring gene prolactin regulatory element binding Neighboring gene transcription factor 23 Neighboring gene all-trans retinoic acid induced differentiation factor Neighboring gene carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Neighboring gene predicted gene, 38601

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC109689

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables biotin transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables pantothenate transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables sodium-dependent multivitamin transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables sodium-dependent multivitamin transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables vitamin transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in biotin import across plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in biotin transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in biotin transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in iodide transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in pantothenate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in pantothenate transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sodium ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in transport across blood-brain barrier ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in brush border membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in vesicle membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    sodium-dependent multivitamin transporter
    Names
    Na(+)-dependent multivitamin transporter
    solute carrier family 5 member 6

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001177621.1NP_001171092.1  sodium-dependent multivitamin transporter

      See identical proteins and their annotated locations for NP_001171092.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. All four variants encode the same protein.
      Source sequence(s)
      AK158896, BC085132
      Consensus CDS
      CCDS19169.1
      UniProtKB/Swiss-Prot
      Q5U4D8
      UniProtKB/TrEMBL
      Q3TY45
      Related
      ENSMUSP00000110316.2, ENSMUST00000114668.7
      Conserved Domains (1) summary
      cl00456
      Location:23548
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    2. NM_001177622.1NP_001171093.1  sodium-dependent multivitamin transporter

      See identical proteins and their annotated locations for NP_001171093.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All four variants encode the same protein.
      Source sequence(s)
      BC065061, BC085132
      Consensus CDS
      CCDS19169.1
      UniProtKB/Swiss-Prot
      Q5U4D8
      Related
      ENSMUSP00000079291.2, ENSMUST00000080431.8
      Conserved Domains (1) summary
      cl00456
      Location:23548
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    3. NM_001360022.1NP_001346951.1  sodium-dependent multivitamin transporter

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. All four variants encode the same protein.
      Source sequence(s)
      AC109608
      Consensus CDS
      CCDS19169.1
      Related
      ENSMUSP00000143993.2, ENSMUST00000202556.4
      Conserved Domains (1) summary
      cl00456
      Location:23548
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    4. NM_177870.5NP_808538.1  sodium-dependent multivitamin transporter

      See identical proteins and their annotated locations for NP_808538.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All four variants encode the same protein.
      Source sequence(s)
      AC109608, AK161633, BC085132
      Consensus CDS
      CCDS19169.1
      UniProtKB/Swiss-Prot
      Q5U4D8
      Related
      ENSMUSP00000143938.2, ENSMUST00000202520.4
      Conserved Domains (1) summary
      cl00456
      Location:23548
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      31193380..31206268 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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