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    Ep300 E1A binding protein p300 [ Mus musculus (house mouse) ]

    Gene ID: 328572, updated on 16-Aug-2021

    Summary

    Official Symbol
    Ep300provided by MGI
    Official Full Name
    E1A binding protein p300provided by MGI
    Primary source
    MGI:MGI:1276116
    See related
    Ensembl:ENSMUSG00000055024
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    p30; KAT3; p300; KAT3B; p300 HAT; A430090G16; A730011L11
    Expression
    Ubiquitous expression in thymus adult (RPKM 18.7), spleen adult (RPKM 16.4) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ep300 in Genome Data Viewer
    Location:
    15; 15 E1
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (81470329..81536278)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (81586209..81652077)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (81416644..81482507)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene ring-box 1 Neighboring gene predicted gene 5218 Neighboring gene RIKEN cDNA 1110025M09 gene Neighboring gene predicted gene, 22067 Neighboring gene L3MBTL2 polycomb repressive complex 1 subunit Neighboring gene TM2 domain containing 1 pseudogene Neighboring gene chondroadherin-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables DNA-binding transcription activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA-binding transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables H3 histone acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables H4 histone acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables NF-kappaB binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables RNA polymerase II-specific DNA-binding transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables STAT family protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables acetyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables acyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables androgen receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables beta-catenin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables chromatin DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables chromatin DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables damaged DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables histone acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables histone acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone acetyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables histone butyryltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables histone crotonyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone lactyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables lysine N-acetyltransferase activity, acting on acetyl phosphate as donor ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nuclear receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables p53 binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables peptide butyryltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables peptide-lysine-N-acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables pre-mRNA intronic binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein C-terminus binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein propionyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transcription coactivator activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription coactivator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables transcription coactivator binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transcription coregulator binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within B cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in N-terminal peptidyl-lysine acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in N-terminal peptidyl-lysine acetylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    acts_upstream_of_or_within animal organ morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in behavioral defense response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cartilage development NAS
    Non-traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular response to UV ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in circadian rhythm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in face morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in fat cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within heart development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in histone H2B acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within histone H3-K56 acetylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in histone H4 acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in histone H4 acetylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in histone acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in histone acetylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in histone acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in internal peptidyl-lysine acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in internal protein amino acid acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in learning or memory IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within lung development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in macrophage derived foam cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within megakaryocyte development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in multicellular organism growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of gluconeogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of protein-containing complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in peptidyl-lysine acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in peptidyl-lysine butyrylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in peptidyl-lysine butyrylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in peptidyl-lysine crotonylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in peptidyl-lysine propionylation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within platelet formation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within platelet formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation by host of viral transcription ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of DNA-binding transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in positive regulation of NF-kappaB transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of NIK/NF-kappaB signaling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of gene expression IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of gene expression, epigenetic ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of neuron projection development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of transcription, DNA-templated ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in positive regulation of transforming growth factor beta receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein acetylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in protein acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein destabilization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein stabilization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of androgen receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of glycolytic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of mitochondrion organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of tubulin deacetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to estrogen ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to hypoxia ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to hypoxia ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    acts_upstream_of_or_within rhythmic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within skeletal muscle tissue development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within somitogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in swimming IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in thigmotaxis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    part_of histone acetyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of histone acetyltransferase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    part_of protein-containing complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of transcription regulator complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    histone acetyltransferase p300
    Names
    E1A-associated protein p300
    histone butyryltransferase p300
    histone crotonyltransferase p300
    protein 2-hydroxyisobutyryltransferase p300
    protein lactyltransferas p300
    protein propionyltransferase p300
    NP_808489.4
    XP_006521152.1
    XP_006521153.1
    XP_006521154.1
    XP_030104471.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177821.6NP_808489.4  histone acetyltransferase p300

      See identical proteins and their annotated locations for NP_808489.4

      Status: VALIDATED

      Source sequence(s)
      AC102262, AK042627, AK139715, BU701221, BY076076, CD348567, CN535246
      Consensus CDS
      CCDS37149.1
      UniProtKB/Swiss-Prot
      B2RWS6
      UniProtKB/TrEMBL
      Q8BJ14
      Related
      ENSMUSP00000066789.5, ENSMUST00000068387.11
      Conserved Domains (12) summary
      cd05495
      Location:10501157
      Bromo_cbp_like; Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to ...
      TIGR01628
      Location:714848
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      smart00551
      Location:17281806
      ZnF_TAZ; TAZ zinc finger, present in p300 and CBP
      cd02337
      Location:16671707
      ZZ_CBP; Zinc finger, ZZ type. Zinc finger present in CBP/p300 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. CREB-binding protein (CBP) is a large multidomain protein that ...
      cd15802
      Location:11691241
      RING_CBP-p300; atypical RING domain found in CREB-binding protein and p300 histone acetyltransferases
      cd15646
      Location:12421276
      PHD_p300; PHD finger found in histone acetyltransferase p300
      pfam07133
      Location:9591048
      Merozoite_SPAM; Merozoite surface protein (SPAM)
      pfam09606
      Location:19582334
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02135
      Location:348415
      zf-TAZ; TAZ zinc finger
      pfam02172
      Location:567647
      KIX; KIX domain
      pfam08214
      Location:13051516
      HAT_KAT11; Histone acetylation protein
      pfam09030
      Location:20062099
      Creb_binding; Creb binding

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      81470329..81536278
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006521089.3XP_006521152.1  histone acetyltransferase p300 isoform X1

      Conserved Domains (12) summary
      cd05495
      Location:10501157
      Bromo_cbp_like; Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to ...
      TIGR01628
      Location:714848
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      smart00551
      Location:17381816
      ZnF_TAZ; TAZ zinc finger, present in p300 and CBP
      cd02337
      Location:16771717
      ZZ_CBP; Zinc finger, ZZ type. Zinc finger present in CBP/p300 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. CREB-binding protein (CBP) is a large multidomain protein that ...
      cd15802
      Location:11691251
      RING_CBP-p300; atypical RING domain found in CREB-binding protein and p300 histone acetyltransferases
      cd15646
      Location:12521286
      PHD_p300; PHD finger found in histone acetyltransferase p300
      pfam07133
      Location:9591048
      Merozoite_SPAM; Merozoite surface protein (SPAM)
      pfam09606
      Location:19682344
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02135
      Location:348415
      zf-TAZ; TAZ zinc finger
      pfam02172
      Location:567647
      KIX; KIX domain
      pfam08214
      Location:13151526
      HAT_KAT11; Histone acetylation protein
      pfam09030
      Location:20162109
      Creb_binding; Creb binding
    2. XM_006521090.4XP_006521153.1  histone acetyltransferase p300 isoform X2

      Conserved Domains (12) summary
      cd05495
      Location:10501150
      Bromo_cbp_like; Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to ...
      TIGR01628
      Location:714848
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      smart00551
      Location:17311809
      ZnF_TAZ; TAZ zinc finger, present in p300 and CBP
      cd02337
      Location:16701710
      ZZ_CBP; Zinc finger, ZZ type. Zinc finger present in CBP/p300 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. CREB-binding protein (CBP) is a large multidomain protein that ...
      cd15802
      Location:11621244
      RING_CBP-p300; atypical RING domain found in CREB-binding protein and p300 histone acetyltransferases
      cd15646
      Location:12451279
      PHD_p300; PHD finger found in histone acetyltransferase p300
      pfam07133
      Location:9591048
      Merozoite_SPAM; Merozoite surface protein (SPAM)
      pfam09606
      Location:19612337
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02135
      Location:348415
      zf-TAZ; TAZ zinc finger
      pfam02172
      Location:567647
      KIX; KIX domain
      pfam08214
      Location:13081519
      HAT_KAT11; Histone acetylation protein
      pfam09030
      Location:20092102
      Creb_binding; Creb binding
    3. XM_030248611.2XP_030104471.1  histone acetyltransferase p300 isoform X3

      Conserved Domains (12) summary
      cd05495
      Location:10501150
      Bromo_cbp_like; Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to ...
      TIGR01628
      Location:714848
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      smart00551
      Location:17211799
      ZnF_TAZ; TAZ zinc finger, present in p300 and CBP
      cd02337
      Location:16601700
      ZZ_CBP; Zinc finger, ZZ type. Zinc finger present in CBP/p300 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. CREB-binding protein (CBP) is a large multidomain protein that ...
      cd15802
      Location:11621234
      RING_CBP-p300; atypical RING domain found in CREB-binding protein and p300 histone acetyltransferases
      cd15646
      Location:12351269
      PHD_p300; PHD finger found in histone acetyltransferase p300
      pfam07133
      Location:9591048
      Merozoite_SPAM; Merozoite surface protein (SPAM)
      pfam09606
      Location:19512327
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02135
      Location:348415
      zf-TAZ; TAZ zinc finger
      pfam02172
      Location:567647
      KIX; KIX domain
      pfam08214
      Location:12981509
      HAT_KAT11; Histone acetylation protein
      pfam09030
      Location:19992092
      Creb_binding; Creb binding
    4. XM_006521091.4XP_006521154.1  histone acetyltransferase p300 isoform X4

      Conserved Domains (12) summary
      cd05495
      Location:10041111
      Bromo_cbp_like; Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to ...
      TIGR01628
      Location:668802
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      smart00551
      Location:16921770
      ZnF_TAZ; TAZ zinc finger, present in p300 and CBP
      cd02337
      Location:16311671
      ZZ_CBP; Zinc finger, ZZ type. Zinc finger present in CBP/p300 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. CREB-binding protein (CBP) is a large multidomain protein that ...
      cd15802
      Location:11231205
      RING_CBP-p300; atypical RING domain found in CREB-binding protein and p300 histone acetyltransferases
      cd15646
      Location:12061240
      PHD_p300; PHD finger found in histone acetyltransferase p300
      pfam07133
      Location:9131002
      Merozoite_SPAM; Merozoite surface protein (SPAM)
      pfam09606
      Location:19222298
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam02135
      Location:348415
      zf-TAZ; TAZ zinc finger
      pfam02172
      Location:543601
      KIX; KIX domain
      pfam08214
      Location:12691480
      HAT_KAT11; Histone acetylation protein
      pfam09030
      Location:19702063
      Creb_binding; Creb binding
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