Format

Send to:

Choose Destination
    • Showing Current items.

    Mysm1 myb-like, SWIRM and MPN domains 1 [ Mus musculus (house mouse) ]

    Gene ID: 320713, updated on 20-Jul-2021

    Summary

    Official Symbol
    Mysm1provided by MGI
    Official Full Name
    myb-like, SWIRM and MPN domains 1provided by MGI
    Primary source
    MGI:MGI:2444584
    See related
    Ensembl:ENSMUSG00000062627
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C130067A03Rik; C530050H10Rik
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 5.5), CNS E11.5 (RPKM 4.6) and 26 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Mysm1 in Genome Data Viewer
    Location:
    4; 4 C5
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (94830274..94867392, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (94942037..94979155, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (94608732..94645791, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene equatorin, sperm acrosome associated Neighboring gene predicted gene 12693 Neighboring gene predicted gene 12694 Neighboring gene jun proto-oncogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables isopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metallopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables metallopeptidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables thiol-dependent deubiquitinase IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables thiol-dependent deubiquitinase ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    deubiquitinase MYSM1; histone H2A deubiquitinase MYSM1
    Names
    2A-DUB
    myb-like, SWIRM and MPN domain-containing protein 1
    NP_796213.2
    XP_006503233.2
    XP_017175747.1
    XP_017175748.1
    XP_017175749.1
    XP_017175750.1
    XP_030109470.1
    XP_030109472.1
    XP_036020079.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177239.3NP_796213.2  deubiquitinase MYSM1

      See identical proteins and their annotated locations for NP_796213.2

      Status: VALIDATED

      Source sequence(s)
      AL732611
      Consensus CDS
      CCDS18363.1
      UniProtKB/Swiss-Prot
      Q69Z66
      Related
      ENSMUSP00000075269.4, ENSMUST00000075872.4
      Conserved Domains (4) summary
      cd08067
      Location:562744
      MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
      smart00717
      Location:117161
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:117160
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam04433
      Location:373452
      SWIRM; SWIRM domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      94830274..94867392 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006503170.4XP_006503233.2  histone H2A deubiquitinase MYSM1 isoform X7

      Conserved Domains (3) summary
      cd08067
      Location:562705
      MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
      pfam00249
      Location:116160
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam04433
      Location:373452
      SWIRM; SWIRM domain
    2. XM_036164186.1XP_036020079.1  histone H2A deubiquitinase MYSM1 isoform X3

      Conserved Domains (3) summary
      cd08067
      Location:562744
      MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
      pfam00249
      Location:116160
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam04433
      Location:373452
      SWIRM; SWIRM domain
    3. XM_017320261.2XP_017175750.1  histone H2A deubiquitinase MYSM1 isoform X6

      Conserved Domains (3) summary
      cd08067
      Location:562710
      MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
      pfam00249
      Location:116160
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam04433
      Location:373452
      SWIRM; SWIRM domain
    4. XM_017320259.2XP_017175748.1  histone H2A deubiquitinase MYSM1 isoform X2

      Conserved Domains (3) summary
      cd08067
      Location:562749
      MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
      pfam00249
      Location:116160
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam04433
      Location:373452
      SWIRM; SWIRM domain
    5. XM_017320258.2XP_017175747.1  histone H2A deubiquitinase MYSM1 isoform X1

      Conserved Domains (3) summary
      cd08067
      Location:562749
      MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
      pfam00249
      Location:116160
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam04433
      Location:373452
      SWIRM; SWIRM domain
    6. XM_030253612.2XP_030109472.1  histone H2A deubiquitinase MYSM1 isoform X8

      Conserved Domains (2) summary
      cd08067
      Location:313495
      MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
      pfam04433
      Location:124203
      SWIRM; SWIRM domain
    7. XM_030253610.2XP_030109470.1  histone H2A deubiquitinase MYSM1 isoform X5

      Conserved Domains (3) summary
      cd08067
      Location:562705
      MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
      pfam00249
      Location:116160
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam04433
      Location:373452
      SWIRM; SWIRM domain
    8. XM_017320260.3XP_017175749.1  histone H2A deubiquitinase MYSM1 isoform X4

      Conserved Domains (3) summary
      cd08067
      Location:562710
      MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
      pfam00249
      Location:116160
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam04433
      Location:373452
      SWIRM; SWIRM domain

    RNA

    1. XR_003954970.2 RNA Sequence

    2. XR_003954969.2 RNA Sequence

    3. XR_003954971.2 RNA Sequence

    Support Center