U.S. flag

An official website of the United States government


Send to:

Choose Destination
    • Showing Current items.

    H4c16 H4 histone 16 [ Mus musculus (house mouse) ]

    Gene ID: 320332, updated on 26-Sep-2022


    Official Symbol
    H4c16provided by MGI
    Official Full Name
    H4 histone 16provided by MGI
    Primary source
    See related
    Ensembl:ENSMUSG00000096010 AllianceGenome:MGI:2448443
    Gene type
    protein coding
    RefSeq status
    Mus musculus
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    H4c1; H4c2; H4c3; H4c4; H4c6; H4c8; H4c9; H4-16; H4c11; H4c12; H4c14; H4f16; Hist4h4; B130044J01Rik
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. [provided by RefSeq, Aug 2015]
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See H4c16 in Genome Data Viewer
    6; 6 G1
    Exon count:
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (136780991..136781429, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (136803993..136804431, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene guanylate cyclase 2c Neighboring gene predicted gene, 40411 Neighboring gene H2J.A histone Neighboring gene WW domain binding protein 11 Neighboring gene cDNA sequence BC049715

    Genomic regions, transcripts, and products


    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?



    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 


    Products Interactant Other Gene Complex Source Pubs Description

    General gene information



    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
    enables structural constituent of chromatin ISO
    Inferred from Sequence Orthology
    more info
    Component Evidence Code Pubs
    part_of CENP-A containing nucleosome ISO
    Inferred from Sequence Orthology
    more info
    part_of nucleosome ISO
    Inferred from Sequence Orthology
    more info
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info

    General protein information

    Preferred Names
    histone H4
    histone 4, H4
    histone cluster 4, H4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175652.3NP_783583.1  histone H4

      See identical proteins and their annotated locations for NP_783583.1

      Status: REVIEWED

      Source sequence(s)
      Consensus CDS
      P62806, Q9D6Q8
      A0A6P5R0T3, A0A8C6H4M7, B2RTM0
      ENSMUSP00000136357.2, ENSMUST00000179285.3
      Conserved Domains (1) summary
      PLN00035; histone H4; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J


    1. NC_000072.7 Reference GRCm39 C57BL/6J

      136780991..136781429 complement
      GenBank, FASTA, Sequence Viewer (Graphics)