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    Ccdc66 coiled-coil domain containing 66 [ Mus musculus (house mouse) ]

    Gene ID: 320234, updated on 31-Jan-2019

    Summary

    Official Symbol
    Ccdc66provided by MGI
    Official Full Name
    coiled-coil domain containing 66provided by MGI
    Primary source
    MGI:MGI:2443639
    See related
    Ensembl:ENSMUSG00000046753
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    E230015L20Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 6.9), bladder adult (RPKM 6.7) and 21 other tissues See more
    Orthologs

    Genomic context

    See Ccdc66 in Genome Data Viewer
    Location:
    14; 14 A3
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (27480911..27508506, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (28295587..28321646, complement)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene Rho guanine nucleotide exchange factor (GEF) 3 Neighboring gene predicted gene, 34754 Neighboring gene predicted gene, 34702 Neighboring gene transcription activation suppressor Neighboring gene predicted gene 7604 Neighboring gene ELKS/RAB6-interacting/CAST family member 2 Neighboring gene aconitase 2, mitochondrial pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    cell projection organization IEA
    Inferred from Electronic Annotation
    more info
     
    cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    detection of light stimulus involved in visual perception IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    microtubule bundle formation ISO
    Inferred from Sequence Orthology
    more info
     
    post-embryonic retina morphogenesis in camera-type eye IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of protein localization to cilium ISO
    Inferred from Sequence Orthology
    more info
     
    retinal rod cell development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
     
    cilium ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    photoreceptor inner segment IDA
    Inferred from Direct Assay
    more info
    PubMed 
    photoreceptor inner segment ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    coiled-coil domain-containing protein 66

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177111.3NP_796085.3  coiled-coil domain-containing protein 66

      See identical proteins and their annotated locations for NP_796085.3

      Status: VALIDATED

      Source sequence(s)
      BC070471
      Consensus CDS
      CCDS36843.1
      UniProtKB/Swiss-Prot
      Q6NS45
      Related
      ENSMUSP00000153023.1, ENSMUST00000223689.1
      Conserved Domains (1) summary
      pfam15236
      Location:407559
      CCDC66; Coiled-coil domain-containing protein 66

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      27480911..27508506 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006519131.3XP_006519194.1  coiled-coil domain-containing protein 66 isoform X3

      UniProtKB/Swiss-Prot
      Q6NS45
      Related
      ENSMUSP00000052546.7, ENSMUST00000050480.7
      Conserved Domains (1) summary
      pfam15236
      Location:251403
      CCDC66; Coiled-coil domain-containing protein 66
    2. XM_006519127.3XP_006519190.1  coiled-coil domain-containing protein 66 isoform X1

      UniProtKB/Swiss-Prot
      Q6NS45
      Conserved Domains (1) summary
      pfam15236
      Location:374526
      CCDC66; Coiled-coil domain-containing protein 66
    3. XM_017316057.1XP_017171546.1  coiled-coil domain-containing protein 66 isoform X2

    4. XM_011245087.1XP_011243389.1  coiled-coil domain-containing protein 66 isoform X4

      Conserved Domains (1) summary
      pfam15236
      Location:407559
      CCDC66; Coiled-coil domain-containing protein 66
    5. XM_011245088.2XP_011243390.1  coiled-coil domain-containing protein 66 isoform X5

      Conserved Domains (1) summary
      pfam15236
      Location:407559
      CCDC66; Coiled-coil domain-containing protein 66
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