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    Msrb3 methionine sulfoxide reductase B3 [ Mus musculus (house mouse) ]

    Gene ID: 320183, updated on 12-Aug-2018

    Summary

    Official Symbol
    Msrb3provided by MGI
    Official Full Name
    methionine sulfoxide reductase B3provided by MGI
    Primary source
    MGI:MGI:2443538
    See related
    Ensembl:ENSMUSG00000051236 Vega:OTTMUSG00000027726
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MsrB2; I-8-23; D430026P16Rik
    Expression
    Biased expression in bladder adult (RPKM 52.3), heart adult (RPKM 20.8) and 14 other tissues See more
    Orthologs

    Genomic context

    See Msrb3 in Genome Data Viewer
    Location:
    10; 10 D2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (120781096..120899215, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (120218156..120336027, complement)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4921513I03 gene Neighboring gene predicted gene, 35182 Neighboring gene predicted gene 15910 Neighboring gene predicted gene 4473 Neighboring gene ribosomal protein L7A pseudogene Neighboring gene LEM domain containing 3 Neighboring gene uncharacterized LOC108167760

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    L-methionine-(R)-S-oxide reductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor IEA
    Inferred from Electronic Annotation
    more info
     
    peptide-methionine (R)-S-oxide reductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    peptide-methionine (R)-S-oxide reductase activity ISO
    Inferred from Sequence Orthology
    more info
     
    peptide-methionine (R)-S-oxide reductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    cellular response to oxidative stress IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    protein repair ISO
    Inferred from Sequence Orthology
    more info
     
    protein repair ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    NOT mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    methionine-R-sulfoxide reductase B3, mitochondrial
    NP_796066.1
    XP_006513826.1
    XP_006513827.1
    XP_006513829.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177092.4NP_796066.1  methionine-R-sulfoxide reductase B3, mitochondrial

      See identical proteins and their annotated locations for NP_796066.1

      Status: VALIDATED

      Source sequence(s)
      AK086975, BB617432, BC096447
      Consensus CDS
      CCDS24208.1
      UniProtKB/Swiss-Prot
      Q8BU85
      UniProtKB/TrEMBL
      A0A0R4J139
      Related
      ENSMUSP00000089781.5, OTTMUSP00000034729, ENSMUST00000092143.11, OTTMUST00000068610
      Conserved Domains (1) summary
      PRK00222
      Location:35171
      PRK00222; methionine sulfoxide reductase B; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      120781096..120899215 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513764.3XP_006513827.1  methionine-R-sulfoxide reductase B3, mitochondrial isoform X2

      See identical proteins and their annotated locations for XP_006513827.1

      UniProtKB/Swiss-Prot
      Q8BU85
      Conserved Domains (1) summary
      PRK00222
      Location:102238
      PRK00222; methionine sulfoxide reductase B; Provisional
    2. XM_006513763.3XP_006513826.1  methionine-R-sulfoxide reductase B3, mitochondrial isoform X1

      Conserved Domains (1) summary
      cl15841
      Location:163249
      SelR; SelR domain
    3. XM_006513766.3XP_006513829.1  methionine-R-sulfoxide reductase B3, mitochondrial isoform X3

      Conserved Domains (1) summary
      cl15841
      Location:86166
      SelR; SelR domain
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