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    Tacc1 transforming, acidic coiled-coil containing protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 320165, updated on 23-May-2018

    Summary

    Official Symbol
    Tacc1provided by MGI
    Official Full Name
    transforming, acidic coiled-coil containing protein 1provided by MGI
    Primary source
    MGI:MGI:2443510
    See related
    Ensembl:ENSMUSG00000065954 Vega:OTTMUSG00000060528
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AA960202; 4833447E04Rik; B230378H13Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 20.7), bladder adult (RPKM 18.6) and 28 other tissues See more
    Orthologs

    Genomic context

    See Tacc1 in Genome Data Viewer
    Location:
    8; 8 A2
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (25154552..25256583, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (26265024..26311921, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2 Neighboring gene predicted gene, 39143 Neighboring gene microRNA 8108 Neighboring gene predicted gene, 39144 Neighboring gene predicted gene, 39145 Neighboring gene RIKEN cDNA 5430421F17 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein domain specific binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    cell proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cerebral cortex development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cerebral cortex development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    interkinetic nuclear migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neurogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of microtubule-based process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    transforming acidic coiled-coil-containing protein 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177089.5NP_796063.3  transforming acidic coiled-coil-containing protein 1 long isoform

      See identical proteins and their annotated locations for NP_796063.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the long isoform.
      Source sequence(s)
      AC114589, AK148214, AK158441, AY177413, BU757900
      Consensus CDS
      CCDS40303.1
      UniProtKB/Swiss-Prot
      Q6Y685
      UniProtKB/TrEMBL
      F8VQ95
      Related
      ENSMUSP00000081043.4, OTTMUSP00000077014, ENSMUST00000084030.5, OTTMUST00000148067
      Conserved Domains (3) summary
      pfam05010
      Location:570769
      TACC; Transforming acidic coiled-coil-containing protein (TACC)
      pfam09403
      Location:675768
      FadA; Adhesion protein FadA
      cl21478
      Location:577662
      ATP-synt_B; ATP synthase B/B' CF(0)
    2. NM_199323.3NP_955355.1  transforming acidic coiled-coil-containing protein 1 short isoform

      See identical proteins and their annotated locations for NP_955355.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. This encodes the short isoform, compared to the long isoform.
      Source sequence(s)
      AC114589, AK148214, AK158441, AY177412, BU757900
      Consensus CDS
      CCDS40302.1
      UniProtKB/Swiss-Prot
      Q6Y685
      Related
      ENSMUSP00000081560.4, OTTMUSP00000077013, ENSMUST00000084512.10, OTTMUST00000148066
      Conserved Domains (1) summary
      pfam05010
      Location:162361
      TACC; Transforming acidic coiled-coil-containing protein (TACC)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      25154552..25256583 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017312859.1XP_017168348.1  transforming acidic coiled-coil-containing protein 1 isoform X2

    2. XM_006509146.3XP_006509209.1  transforming acidic coiled-coil-containing protein 1 isoform X3

      Conserved Domains (1) summary
      pfam05010
      Location:121320
      TACC; Transforming acidic coiled-coil-containing protein (TACC)
    3. XM_006509147.3XP_006509210.1  transforming acidic coiled-coil-containing protein 1 isoform X4

      Conserved Domains (1) summary
      pfam05010
      Location:117316
      TACC; Transforming acidic coiled-coil-containing protein (TACC)
    4. XM_006509143.3XP_006509206.1  transforming acidic coiled-coil-containing protein 1 isoform X1

      Conserved Domains (3) summary
      pfam05010
      Location:582781
      TACC; Transforming acidic coiled-coil-containing protein (TACC)
      pfam09403
      Location:687780
      FadA; Adhesion protein FadA
      cl21478
      Location:589674
      ATP-synt_B; ATP synthase B/B' CF(0)
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