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    Cep95 centrosomal protein 95 [ Mus musculus (house mouse) ]

    Gene ID: 320162, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cep95provided by MGI
    Official Full Name
    centrosomal protein 95provided by MGI
    Primary source
    MGI:MGI:2443502
    See related
    Ensembl:ENSMUSG00000018372
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ccdc45; AI118346; AI448335; 4732496G21Rik; D330027A14Rik; F630025I20Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 9.1), CNS E11.5 (RPKM 8.2) and 26 other tissues See more
    Orthologs

    Genomic context

    See Cep95 in Genome Data Viewer
    Location:
    11; 11 E1
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (106789226..106818861)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (106650566..106680175)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene mast cell immunoglobulin like receptor 1 Neighboring gene polymerase (DNA directed), gamma 2, accessory subunit Neighboring gene microRNA 3064 Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 Neighboring gene SMAD specific E3 ubiquitin protein ligase 2 Neighboring gene Smad nuclear interacting protein 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    spindle pole ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    centrosomal protein of 95 kDa
    Names
    coiled-coil domain containing 45
    coiled-coil domain-containing protein 45

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166685.1NP_001160157.1  centrosomal protein of 95 kDa isoform 2

      See identical proteins and their annotated locations for NP_001160157.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate coding exon but maintains the reading frame compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1.
      Source sequence(s)
      AK052705, BC090675, BE852789, BU695983
      Consensus CDS
      CCDS48963.1
      UniProtKB/TrEMBL
      Q14B65, Q8BWE9
      Related
      ENSMUSP00000099357.3, ENSMUST00000103068.9
      Conserved Domains (1) summary
      TIGR02168
      Location:541773
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    2. NM_177088.3NP_796062.2  centrosomal protein of 95 kDa isoform 1

      See identical proteins and their annotated locations for NP_796062.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK052705, BC090675, BE852789, BU695983
      Consensus CDS
      CCDS25563.1
      UniProtKB/Swiss-Prot
      Q8BVV7
      UniProtKB/TrEMBL
      Q8BWE9
      Related
      ENSMUSP00000018516.4, ENSMUST00000018516.10
      Conserved Domains (2) summary
      PHA03307
      Location:191360
      PHA03307; transcriptional regulator ICP4; Provisional
      TIGR02168
      Location:584816
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      106789226..106818861
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006533544.2XP_006533607.1  centrosomal protein of 95 kDa isoform X1

      Conserved Domains (2) summary
      PHA03307
      Location:191360
      PHA03307; transcriptional regulator ICP4; Provisional
      TIGR02168
      Location:541773
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    2. XM_017314609.1XP_017170098.1  centrosomal protein of 95 kDa isoform X2

    RNA

    1. XR_879703.2 RNA Sequence

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