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    H2bc1 H2B clustered histone 1 [ Mus musculus (house mouse) ]

    Gene ID: 319177, updated on 23-Jun-2021

    Summary

    Official Symbol
    H2bc1provided by MGI
    Official Full Name
    H2B clustered histone 1provided by MGI
    Primary source
    MGI:MGI:2448375
    See related
    Ensembl:ENSMUSG00000050799
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Th2b; Hist1h; Hist1h2ba
    Summary
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]
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    Genomic context

    See H2bc1 in Genome Data Viewer
    Location:
    13; 13 A3.1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (24117708..24118139, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (23933725..23934156, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (24025642..24026025, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 17 (sodium phosphate), member 4 Neighboring gene U1 small nuclear ribonucleoprotein 1C, pseudogene 2 Neighboring gene predicted gene, 33516 Neighboring gene H2A clustered histone 1 Neighboring gene secretagogin, EF-hand calcium binding protein

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables histone binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of DNA packaging complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extrinsic component of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    part_of nucleosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of nucleosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    histone H2B type 1-A
    Names
    histone 1, H2ba
    histone H2B, testis
    histone cluster 1, H2ba
    testis-specific histone H2B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175663.2NP_783594.1  histone H2B type 1-A

      See identical proteins and their annotated locations for NP_783594.1

      Status: REVIEWED

      Source sequence(s)
      AL606464
      Consensus CDS
      CCDS26373.1
      UniProtKB/Swiss-Prot
      P70696
      Related
      ENSMUSP00000056604.3, ENSMUST00000052776.4
      Conserved Domains (1) summary
      smart00427
      Location:29125
      H2B; Histone H2B

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      24117708..24118139 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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