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    H2ac1 H2A clustered histone 1 [ Mus musculus (house mouse) ]

    Gene ID: 319163, updated on 26-Sep-2022


    Official Symbol
    H2ac1provided by MGI
    Official Full Name
    H2A clustered histone 1provided by MGI
    Primary source
    See related
    Ensembl:ENSMUSG00000060081 AllianceGenome:MGI:2448285
    Gene type
    protein coding
    RefSeq status
    Mus musculus
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Th2a; Hist1h2aa
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]
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    Genomic context

    See H2ac1 in Genome Data Viewer
    13; 13 A3.1
    Exon count:
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (24118420..24118896)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (23934437..23934913)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene U1 small nuclear ribonucleoprotein 1C, pseudogene 2 Neighboring gene predicted gene, 33516 Neighboring gene H2B clustered histone 1 Neighboring gene secretagogin, EF-hand calcium binding protein Neighboring gene capping protein regulator and myosin 1 linker 1 Neighboring gene predicted gene, 33573

    Genomic regions, transcripts, and products


    General gene information


    Clone Names

    • MGC130330, MGC130331

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    Process Evidence Code Pubs
    acts_upstream_of_or_within chromatin organization IDA
    Inferred from Direct Assay
    more info
    Component Evidence Code Pubs
    located_in female germ cell nucleus IDA
    Inferred from Direct Assay
    more info

    General protein information

    Preferred Names
    histone cluster 1, H2aa
    histone 1, H2aa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175658.3NP_783589.1  histone cluster 1, H2aa

      See identical proteins and their annotated locations for NP_783589.1

      Status: REVIEWED

      Source sequence(s)
      Consensus CDS
      A0A8C6IAE0, Q8CGP4
      ENSMUSP00000072227.2, ENSMUST00000072391.2
      Conserved Domains (2) summary
      PTZ00017; histone H2A; Provisional
      H2A; Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J


    1. NC_000079.7 Reference GRCm39 C57BL/6J

      GenBank, FASTA, Sequence Viewer (Graphics)