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    TAAR6 trace amine associated receptor 6 [ Homo sapiens (human) ]

    Gene ID: 319100, updated on 5-Mar-2024

    Summary

    Official Symbol
    TAAR6provided by HGNC
    Official Full Name
    trace amine associated receptor 6provided by HGNC
    Primary source
    HGNC:HGNC:20978
    See related
    Ensembl:ENSG00000146383 MIM:608923; AllianceGenome:HGNC:20978
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    TA4; TAR4; TAR6; TRAR4; taR-4; taR-6
    Summary
    This gene encodes a seven-transmembrane G-protein-coupled receptor that likely functions as a receptor for endogenous trace amines. Mutations in this gene may be associated with schizophrenia.[provided by RefSeq, Feb 2010]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See TAAR6 in Genome Data Viewer
    Location:
    6q23.2
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (132570322..132571359)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (133765283..133766320)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (132891461..132892498)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene trace amine associated receptor 8 Neighboring gene trace amine associated receptor 7, pseudogene Neighboring gene trace amine associated receptor 5 Neighboring gene trace amine associated receptor 4, pseudogene Neighboring gene trace amine associated receptor 3, pseudogene

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    enables trace-amine receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    trace amine-associated receptor 6
    Names
    trace amine receptor 4
    trace amine receptor 6

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_016544.1 RefSeqGene

      Range
      5001..6038
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_175067.1NP_778237.1  trace amine-associated receptor 6

      See identical proteins and their annotated locations for NP_778237.1

      Status: REVIEWED

      Source sequence(s)
      AY183470
      Consensus CDS
      CCDS5155.1
      UniProtKB/Swiss-Prot
      Q5VUQ4, Q96RI8
      Related
      ENSP00000275198.1, ENST00000275198.1
      Conserved Domains (2) summary
      pfam00001
      Location:49311
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:43271
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      132570322..132571359
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      133765283..133766320
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)