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    Sec22a SEC22 homolog A, vesicle trafficking protein [ Mus musculus (house mouse) ]

    Gene ID: 317717, updated on 26-Sep-2022

    Summary

    Official Symbol
    Sec22aprovided by MGI
    Official Full Name
    SEC22 homolog A, vesicle trafficking proteinprovided by MGI
    Primary source
    MGI:MGI:2447876
    See related
    Ensembl:ENSMUSG00000034473 AllianceGenome:MGI:2447876
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sec22l2; 1810005C06Rik
    Summary
    Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to act upstream of or within protein transport and vesicle-mediated transport. Predicted to be integral component of membrane. Orthologous to human SEC22A (SEC22 homolog A, vesicle trafficking protein). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in placenta adult (RPKM 4.6), bladder adult (RPKM 4.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Sec22a in Genome Data Viewer
    Location:
    16; 16 B3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (35131501..35184299, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (35311131..35363929, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53952 Neighboring gene 3-hydroxyacyl-CoA dehydratase 2 Neighboring gene adenylate cyclase 5 Neighboring gene predicted gene, 46550 Neighboring gene predicted gene, 25179 Neighboring gene predicted gene, 25079 Neighboring gene predicted gene, 23518

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    vesicle-trafficking protein SEC22a
    Names
    SEC22 vesicle trafficking protein homolog A
    SEC22 vesicle trafficking protein homologe A
    SEC22 vesicle trafficking protein-like 2
    SEC22 vesicle trafficking protein-like A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133704.4NP_598465.2  vesicle-trafficking protein SEC22a

      See identical proteins and their annotated locations for NP_598465.2

      Status: PROVISIONAL

      Source sequence(s)
      AC154654
      Consensus CDS
      CCDS28138.1
      UniProtKB/Swiss-Prot
      Q8BH47, Q91Z54
      UniProtKB/TrEMBL
      B2RSR2
      Related
      ENSMUSP00000039568.5, ENSMUST00000043521.5
      Conserved Domains (2) summary
      COG5143
      Location:4146
      SNC1; Synaptobrevin/VAMP-like protein [Intracellular trafficking and secretion]
      pfam13774
      Location:3898
      Longin; Regulated-SNARE-like domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      35131501..35184299 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006522234.4XP_006522297.2  vesicle-trafficking protein SEC22a isoform X1

      See identical proteins and their annotated locations for XP_006522297.2

      UniProtKB/TrEMBL
      A0A6P7QP39, B7ZNW3
      Related
      ENSMUSP00000156164.2, ENSMUST00000232420.2
      Conserved Domains (1) summary
      cd14824
      Location:5126
      Longin; longin domain
    2. XM_006522235.4XP_006522298.1  vesicle-trafficking protein SEC22a isoform X2

      UniProtKB/TrEMBL
      A0A8C6GSK8
      Conserved Domains (1) summary
      cd14824
      Location:21142
      Longin; longin domain