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    snz snazarus [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31704, updated on 18-Sep-2024

    Summary

    Official Symbol
    snzprovided by FlyBase
    Official Full Name
    snazarusprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029976
    Locus tag
    Dmel_CG1514
    See related
    AllianceGenome:FB:FBgn0029976
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1514; Dmel\CG1514; DmSNX25; Snz; SNZ
    Summary
    Enables phosphatidylinositol-3,4-bisphosphate binding activity and phospholipid binding activity. Involved in determination of adult lifespan; lipid homeostasis; and lipid transport involved in lipid storage. Located in cell body membrane and endoplasmic reticulum. Is expressed in adult fat body; adult head; and embryonic/larval fat body. Orthologous to human SNX25 (sorting nexin 25). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See snz in Genome Data Viewer
    Location:
    7C2-7C3; 1-21 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (7912089..7918444)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (7806122..7812477)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene defective proboscis extension response 14 Neighboring gene spidey Neighboring gene hold'em Neighboring gene YKT6 v-SNARE

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables phosphatidylinositol binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylinositol-3,4,5-trisphosphate binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables phosphatidylinositol-3,4-bisphosphate binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables phosphatidylinositol-3,5-bisphosphate binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables phosphatidylinositol-4,5-bisphosphate binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables phosphatidylserine binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables phospholipid binding ISM
    Inferred from Sequence Model
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cell body membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    PubMed 

    General protein information

    Preferred Names
    snazarus
    Names
    CG1514-PA
    CG1514-PB
    snz-PA
    snz-PB

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      7912089..7918444
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298064.1NP_001284993.1  snazarus, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284993.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T4E8, Q9W3N0
      Conserved Domains (4) summary
      cd06878
      Location:645788
      PX_SNX25; The phosphoinositide binding Phox Homology domain of Sorting Nexin 25
      cd08720
      Location:422531
      RGS_SNX25; Regulator of G protein signaling (RGS) domain found in the Sorting Nexin 25 (SNX25) protein
      pfam02194
      Location:142299
      PXA; PXA domain
      pfam08628
      Location:882987
      Nexin_C; Sorting nexin C terminal
    2. NM_132193.2NP_572421.1  snazarus, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572421.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T4E8, Q9W3N0
      Related
      FBpp0071048
      Conserved Domains (4) summary
      cd06878
      Location:645788
      PX_SNX25; The phosphoinositide binding Phox Homology domain of Sorting Nexin 25
      cd08720
      Location:422531
      RGS_SNX25; Regulator of G protein signaling (RGS) domain found in the Sorting Nexin 25 (SNX25) protein
      pfam02194
      Location:142299
      PXA; PXA domain
      pfam08628
      Location:882987
      Nexin_C; Sorting nexin C terminal