p115 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: p115provided by FlyBase
Primary source: FLYBASE:FBgn0040087
Locus tag: Dmel_CG1422
See related: AllianceGenome:FB:FBgn0040087
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG1422; Dmel\CG1422; dp115; l(1)G0306
Summary: Involved in Golgi organization; regulation of G2/M transition of mitotic cell cycle; and regulation of imaginal disc-derived wing size. Located in Golgi stack and endoplasmic reticulum. Is expressed in several structures, including anterior ectoderm; anterior ectoderm anlage; embryonic/larval digestive system; foregut primordium; and presumptive embryonic/larval system. Orthologous to human USO1 (USO1 vesicle transport factor). [provided by Alliance of Genome Resources, Apr 2022]
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (7894031..7896991)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (7788064..7791024)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Process	Evidence Code	Pubs
involved_in Golgi organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in Golgi vesicle docking	IBA Inferred from Biological aspect of Ancestor more info
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular protein transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular protein transport	IEA Inferred from Electronic Annotation more info
involved_in male germ-line stem cell population maintenance	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in membrane fusion	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of receptor signaling pathway via JAK-STAT	IGI Inferred from Genetic Interaction more info	PubMed
involved_in regulation of G2/M transition of mitotic cell cycle	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of imaginal disc-derived wing size	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transcytosis	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle fusion with Golgi apparatus	IEA Inferred from Electronic Annotation more info
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in ER to Golgi transport vesicle membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
is_active_in Golgi stack	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi stack	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum	IDA Inferred from Direct Assay more info	PubMed

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