Format

Send to:

Choose Destination
    • Showing Current items.

    Vapa vesicle-associated membrane protein, associated protein A [ Mus musculus (house mouse) ]

    Gene ID: 30960, updated on 8-Oct-2018

    Summary

    Official Symbol
    Vapaprovided by MGI
    Official Full Name
    vesicle-associated membrane protein, associated protein Aprovided by MGI
    Primary source
    MGI:MGI:1353561
    See related
    Ensembl:ENSMUSG00000024091
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    33kDa; VAP33
    Expression
    Ubiquitous expression in duodenum adult (RPKM 108.3), adrenal adult (RPKM 93.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Vapa in Genome Data Viewer
    Location:
    17; 17 E1.1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (65580053..65613939, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (65929393..65962895, complement)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene transmembrane protein 232 Neighboring gene ribosomal protein L18 pseudogene Neighboring gene predicted gene, 35400 Neighboring gene predicted gene, 35477 Neighboring gene thioredoxin domain containing 2 (spermatozoa) Neighboring gene RAB31, member RAS oncogene family

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    FFAT motif binding ISO
    Inferred from Sequence Orthology
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein heterodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    COPII-coated vesicle budding ISO
    Inferred from Sequence Orthology
    more info
     
    ER to Golgi vesicle-mediated transport ISO
    Inferred from Sequence Orthology
    more info
     
    cell death ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation by host of viral genome replication ISO
    Inferred from Sequence Orthology
    more info
     
    neuron projection development ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation by host of viral genome replication ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation by host of viral release from host cell ISO
    Inferred from Sequence Orthology
    more info
     
    protein localization to endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with bicellular tight junction ISO
    Inferred from Sequence Orthology
    more info
     
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    vesicle-associated membrane protein-associated protein A
    Names
    33 kDa VAMP-associated protein
    VAMP-A
    VAMP-associated protein A
    VAP-33
    VAP-A
    synaptobrevin-associated protein of 33kDa

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355402.1NP_001342331.1  vesicle-associated membrane protein-associated protein A isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC166058, CT030729
      Conserved Domains (1) summary
      pfam00635
      Location:14118
      Motile_Sperm; MSP (Major sperm protein) domain
    2. NM_013933.3NP_038961.2  vesicle-associated membrane protein-associated protein A isoform 2

      See identical proteins and their annotated locations for NP_038961.2

      Status: VALIDATED

      Source sequence(s)
      AK167381, BM899396
      Consensus CDS
      CCDS37677.1
      UniProtKB/Swiss-Prot
      Q9WV55
      Related
      ENSMUSP00000024897.8, ENSMUST00000024897.9
      Conserved Domains (1) summary
      pfam00635
      Location:14118
      Motile_Sperm; MSP (Major sperm protein) domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      65580053..65613939 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017317500.1XP_017172989.1  vesicle-associated membrane protein-associated protein A isoform X1

      Related
      ENSMUSP00000156845.1, ENSMUST00000232686.1
    2. XM_006524385.3XP_006524448.1  vesicle-associated membrane protein-associated protein A isoform X2

      Conserved Domains (1) summary
      pfam00635
      Location:14118
      Motile_Sperm; MSP (Major sperm protein) domain
    Support Center