Format

Send to:

Choose Destination
    • Showing Current items.

    Siva1 SIVA1, apoptosis-inducing factor [ Mus musculus (house mouse) ]

    Gene ID: 30954, updated on 31-Jan-2019

    Summary

    Official Symbol
    Siva1provided by MGI
    Official Full Name
    SIVA1, apoptosis-inducing factorprovided by MGI
    Primary source
    MGI:MGI:1353606
    See related
    Ensembl:ENSMUSG00000064326
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Siva; CD27bp
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 53.8), ovary adult (RPKM 52.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Siva1 in Genome Data Viewer
    Location:
    12; 12 F1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (112644828..112649152)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (113883039..113887363)

    Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene adenylosuccinate synthetase like 1 Neighboring gene predicted gene, 30101 Neighboring gene thymoma viral proto-oncogene 1 Neighboring gene microRNA 6939 Neighboring gene predicted gene, 30150

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    CD27 receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    CD27 receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    tumor necrosis factor receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    virus receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    apoptosis regulatory protein Siva
    Names
    CD27-binding protein
    Cd27 binding protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001161737.1NP_001155209.1  apoptosis regulatory protein Siva isoform 2

      See identical proteins and their annotated locations for NP_001155209.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.
      Source sequence(s)
      AC124373, AF033112, AW060433, CB524656
      Consensus CDS
      CCDS49189.1
      UniProtKB/Swiss-Prot
      O54926
      Related
      ENSMUSP00000105377.3, ENSMUST00000109755.4
      Conserved Domains (1) summary
      pfam05458
      Location:1110
      Siva; Cd27 binding protein (Siva)
    2. NM_013929.2NP_038957.2  apoptosis regulatory protein Siva isoform 1

      See identical proteins and their annotated locations for NP_038957.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC124373, AK017570, AW060433, CB524656
      Consensus CDS
      CCDS26193.1
      UniProtKB/Swiss-Prot
      O54926
      Related
      ENSMUSP00000021728.4, ENSMUST00000021728.11
      Conserved Domains (1) summary
      pfam05458
      Location:1175
      Siva; Cd27 binding protein (Siva)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

      Range
      112644828..112649152
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center